線条体ドーパミン機能PET画像の三次元表示

概要

論文の詳細を見る
[^11C] CFT and [^11C] raclopride images obtained by positron emission tomography (PET) are used to evaluate pre-synaptic dopamine transporter availability and post-synaptic dopamine D2 receptor binding, respectively. A combined study with these tracers is useful for the differential diagnosis of Parkinson's disease. We generated three-dimensional (3D) animations of striatum PET images for the diagnosis of Parkinson's disease. Brain images of a normal subject and a typical Parkinson's disease patient with [^11C] CFT and [^11C] raclopride were obtained using a PET camera. Three-dimensional animations were generated from serial maximum intensity projection (MIP) images created by gradually changing the projection angle. Furthermore, the striatum images extracted from brain data were superimposed over a brain surface magnetic resonance (MR) image that was created by the volume-rendering method, and 3D animations were similarly generated. The present 3D animations were clinically useful for the differential diagnosis of brain diseases, because we were able to observe distributions of [^11C] CFT and [^11C] raclopride from any angle and to grasp at a glance the regional differences of distributions in reference to anatomical landmarks.
社団法人日本放射線技術学会の論文
2002-12-20