Structure of the planarian central nervous system (CNS) revealed by neuronal cell markers
スポンサーリンク
概要
- 論文の詳細を見る
Planarians are considered to be among the most primitive animals which developed the central nervous system (CNS). To understand the origin and evolution of the CNS, we have isolated a neural marker gene from a planarian, Dugesia japonica, and analyzed the structure of the planarian CNS by in situ hybridization. The planarian CNS is located on the ventral side of the body, and composed of a mass of cephalic ganglions in the head region and a pair of ventral nerve cords (VNC). Cephalic ganglions cluster independently from VNC, are more dorsal than VNC, and form an inverted U-shaped brain-like structure with nine branches on each outer side. Two eyes are located on the dorsal side of the 3(rd) branch and visual axons form optic chiasma on the dorsal-inside region of the inverted U-shaped brain. The 6(th)-9(th) branches cluster more closely and form auricles on the surface which may function as the sensory organ of taste. We found that the gross structure of the planarian CNS along the anterior-posterior (A-P) axis is strikingly similar to the distribution pattern of the "primary" neurons of vertebrate embryos which differentiate at the neural plate stage to provide a fundamental nervous system, although the vertebrate CNS is located on the dorsal side. These data suggest that the basic plan for the CNS development along the A-P axis might have been acquired at an early stage of evolution before conversion of the location of the CNS from the ventral to the dorsal side.
- 社団法人日本動物学会の論文
著者
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Kato Kentaro
Laboratory Of Regeneration Biology Department Of Life Science Faculty Of Science Himeji Institute Of
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Agata K
Dep. Of Biophysics Graduate School Of Sci. Kyoto Univ.
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Agata Kiyokazu
Lab. Mol. Dev. Biol. Grad. Sch. Sci. Kyoto Univ.
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Agata Kiyokazu
Genome Resource And Analysis Subunit Riken Center For Developmental Biology
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Watanabe Kohei
Canon Inc.
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Agata Kiyokazu
Dep. Of Biophysics Graduate School Of Sci. Kyoto Univ.
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Agata Kiyokazu
Laboratory For Evolutionary Regeneration Center For Developmental Biology Riken
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Watanabe Kenji
Graduate School Of Life Science University Of Hyogo
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Watanabe Kenji
Laboratory of Regeneration Biology, Department of Life Science, Faculty of Science, Himeji Institute
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Soejima Yukihiro
Laboratory of Regeneration Biology, Department of Life Science, Faculty of Science, Himeji Institute
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Kobayashi Chiyoko
Laboratory of Regeneration Biology, Department of Life Science, Faculty of Science, Himeji Institute
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Umesono Yoshihiko
Laboratory of Regeneration Biology, Department of Life Science, Faculty of Science, Himeji Institute
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Agata Kiyokazu
Group For Evolutionary Regeneration Biology Center For Developmental Biology Riken Kobe
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Watanabe Kazutada
Department Of Experimental Biology Tokyo Metropolitan Institute Of Gerontology
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Kato Kentaro
Laboratory Of Cancer Biology And Molecular Immunology Graduate School Of Pharmaceutical Sciences The
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Kobayashi C
Laboratory For Evolutionary Regeneration Biology Center For Developmental Biology Riken Kobe
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Kobayashi Chiyoko
Laboratory For Evolutionary Regeneration Center For Developmental Biology Riken Kobe
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Umesono Y
Group For Evolutionary Regeneration Biology Center For Developmental Biology Riken Kobe
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Soejima Yukihiro
Laboratory Of Regeneration Biology Department Of Life Science Faculty Of Science Himeji Institute Of
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Watanabe Kenji
Laboratory Of Regeneration Biology Department Of Life Science Graduate School Of Science Himeji Inst
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Watanabe Kenji
Laboratory Of Food Material Engineering Faculty Of Agriculture Gifu University
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Kobayashi Chiyoko
Laboratory for Evolutionary Regeneration Biology, Center for Developmental Biology, RIKEN Kobe
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