Erythrocyte Diapedesis in Anterior Pituitary Hemorrhage after Intraperitoneal Injection of Hypertonic Solution in Mice : Endocrinology

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概要

• 論文の詳細を見る

• Initial changes of hemorrhage occurring in the anterior pituitary of mice received ip injection of 9% NaCl at a dose of 0.03ml/g body weight were investigated with the electron microscope. The sinusoidal capillaries were distended and filled with erythrocytes after 10min of the injection. Extravasation of red blood cells took place without distinct injury to the endothelium, being involved in a mechanism known as diapedesis. Two types of passages traversing the endothelium were distinguished in this erythrocyte diapedisis: through the large endothelial gaps up to 1μm in diameter, and the other of, predominantly, through the occluding junctions of adjacent cells of the endothelium. In the latter case, the red blood cell showed thread-like configuration in the middle of the cell body when migrating across the endothelial tight junction. In addition the erythrocyte migration through the zonula occludens of the marginal cells with no obvious structural injury was encountered. The intercellular junctions of the endothelium as well as those of the marginal cells of the anterior pituitary may be provided with the zonula occludens which is very leaky in structure.

• 社団法人日本動物学会の論文
• 1989-04-15

著者

• KOBAYASHI YASUO

  Department of Dentistry Oral Surgery, Nagano Municipal Hospital

• Kobayashi Y

  Shimane Medical Univ. Izumo Jpn

• Kobayashi Y

  Japan Atomic Energy Res. Inst. Takasaki Jpn

• IGA CHIE

  Department of Biology, Faculty of Science, Okayama University

• Iga C

  Okayama Univ. Okayama Jpn

• Iga Chie

  Department Of Biology Faculty Of Science Okayama University

• Kobayashi Yasuo

  Department Of Applied Biochemistry Hiroshima University

• Kobayashi Yasuo

  Department Of Anesthesia Asahikawa City Hospital

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