Effects of Desacetyl-α-MSH on Lipid Mobilization in the Rainbow Trout, Oncorhynchus mykiss : Endocrinology
スポンサーリンク
概要
- 論文の詳細を見る
Effects of melanocyte-stimulating hormone (MSH) and β-endorphin on lipid mobilization were examined in the rainbow trout (Oncorhnchus mykiss). Plasma levels of fatty acid (FA) were measured after intra-arterial administration of α-MSH, desacetyl-α-MSH, β-MSH, or β-endorphin through a cannula in the dorsal aorta. Desacetyl-α-MSH at 1 ng/g body weight resulted in an increase in plasma FA levels 1-3 hr after the injection, whereas the other three peptides showed no significant effect at the same dose. There was no significant change in plasma levels of cortisol after administration of any of the peptides. Lipolytic enzyme activity in the liver was significantly increased in a dose-related manner 1 hr after single intra-peritoneal injection of desacetyl-α-MSH. The direct effect of desacetyl-α-MSH on lipolysis was examined in liver slices incubated in vitro. Lipase activity in the liver slice was stimulated in the medium containing desacetyl-α-MSH in a dose-related manner. The results indicate that desacetyl-α-MSH is a potent stimulator of lipid mobilization in the rainbow trout.
- 社団法人日本動物学会の論文
- 2000-11-01
著者
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HIROSE Shigehisa
Department of Biological Sciences, Tokyo Institute of Technology
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Takahashi Akiyoshi
School Of Marine Biosciences Kitasato University
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Takahashi Akiyoshi
School Of Fisheries Sciences Kitasato Univeristy
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Suzuki Yoshiro
Department Of Biological Science Tokyo Institute Of Technology
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Suzuki Yoshiro
Department Of Applied Physics Faculty Of Engineering Tohoku University
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AZUMA TERUO
Nikko Branch, National Research Institute of Aquaculture
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YADA TAKASHI
Nikko Branch, National Research Institute of Aquaculture
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Hirose Shigehisa
Department Of Biological Science Tokyo Institute Of Technology
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Azuma Teruo
Nikko Branch National Research Institute Of Aquaculture
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Yada T
Jichi Med. Univ. Tochigi
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Yada Takashi
Nikko Branch National Research Institute Of Aquaculture
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Takahashi A
School Of Marine Biosciences Kitasato University
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Suzuki Y
Fisheries Laboratory Graduate School Of Agricultural And Life Sciences The University Of Tokyo
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Hirose S
Department Of Biological Science Tokyo Institute Of Technology
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Azuma T
Nikko Branch National Research Institute Of Aquaculture
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Suzuki Yuzuru
Fisheries Laboratory Graduate School Of Agricultural And Life Sciences University Of Tokyo
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