OBSERVATIONS ON LACTATION WITH SULPIRIDE IN FEMALE RATS
スポンサーリンク
概要
- 論文の詳細を見る
Ultrastructural observations and the histochemical methods for phosphatases (ACPase, ALPase, TPPase, G6Pase, and ATPase), dehydrogenases (SDH, LDH, and G6PDH), and fats were performed on the mammary and adenohypophyseal tissues of adult virgin, diestrous rats, within 48 hr after a single administration of Sulpiride and in a week of the daily injection. A rapid release and the following production of secretory granules could be seen in the prolactin cells of the anterior pituitary gland 6-24 hr after the injection. Acute hyperactivity of the mammary acini and ductuli could be detected 12-24 hr after the single dosage, and a prominent secretion and a marked proliferation could be observed on the mammary gland during the daily injection. Milk congestion in some mammary acini caused finally a pressure atrophy in the corresponding epithelial cells. Both radioimmunoassay for prolactin contents in the serum and the adenohypophysis and radioautography for thymidine uptakes into the mammary and pituitary parenchyms did serve to confirm the "hypothalamic lactation" with the drug.
- 日本組織細胞化学会の論文
著者
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NAGASAWA Hiroshi
Department of Physics, Osaka City University
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Fujii Toshiyuki
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Kaneda Yoshimasa
Department Of Infectious Disease Tokai University School Of Medicine
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Kaneda Yoshimasa
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Morii Sotokichi
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Morii Sotokichi
Department Of Pathology Kansai Medical School
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Ishida Akira
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Fujii Toshiyuki
Department Of Innovative And Engineered Materials Tokyo Institute Of Technology
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KAWAKITA Yozo
Department of Pathology, Kansai Medical University
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Ishida Akira
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Ishida Akira
Department Of Pathology Kansai Medical University
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Ishida Akira
Department Electrical Engineering Faculty Of Engineering Osaka University
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Nagasawa Hiroshi
Department Of Anesthesiology Meikai University School Of Dentistry
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Kawakita Yozo
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Nagasawa Hiroshi
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Morii Sotokichi
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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Morii Sotokichi
Department Of Pathology Kansai Medica1 University
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Fujii Toshiyuki
Department Of Pathology Kansai Medical University:pharmacology Division National Cancer Research Ins
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