Serologic Response to Blastocystis hominis Infection in Asymptomatic Individuals
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概要
- 論文の詳細を見る
The pathogenic potential of Blastocystis hominis in the human intestine is subject to controversy because the organism has been found in both symptomatic and asymptomatic individuals. To help clarify this issue, we monitored the serologic response to the organism in B. hominis-infected individuals free of gastroenterologic disorders. 1) Serum antibodies to B. hominis were detected in 70% of infected asymptomatic individuals by an indirect immunofluorescence (IFA) test. 2) IFA and immunoelectron microscopy revealed that the antibody response was directed against a surface antigen (s) of the organism. 3) Analysis by immunoblotting implicated a 12 kDa protein of B. hominis. 4) The strongest positive reaction was obtained in an individual chronically infected for more than 2 years. It may be that long exposure to the parasite is necessary for a serologic response.
- 東海大学の論文
著者
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Tachibana Hiroshi
Department Of Applied Chemistry Graduate Course Of Urban Environmental Sciences Tokyo Metropolitan U
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Tachibana Hiroshi
Department Of Infectious Diseases Tokai University School Of Medicine
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Tsutsumi Yutaka
Department Of Internal Medicine Hakodate Municipal Hospital
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Kaneda Yoshimasa
Department Of Infectious Disease Tokai University School Of Medicine
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Horiki Noriyuki
Department Of Gastroenterology St Luke's International Hospital
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Horiki Noriyuki
Department Of Internal Medicine St. Luke's International Hospital
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CHENG Xun-Jia
Department of Infectious Diseases, Tokai University School of Medicine
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Cheng Xun-jia
Department Of Infectious Diseases Tokai University School Of Medicine
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