泌尿器系悪I性腫瘍患者における血清蛋白異常 : 第2報臨床経過と血清蛋白の変動

概要

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In our previous report, we demonstrated that there were significant changes in several serum proteins in patients with malignant tumors of the urogenital system and suggested that measurement of these proteins would be helpful for evaluation of the clinical stage in these patients. In this report, we analyzed the changes of the serum proteins such as prealbumin (Pre), α_1-acid glycoprotein (α_1-AG), α_1-antitrypsin (α_1-AT), α_2-HS glycoprotein (α_2-HS), ceruloplasmin (Cp), haptoglobin (Hp) and transfbrrin (Tf), by the quantitative measurement by the use of Behringwerke Partigens, particularly along with the clinical course of 81 cases of malignant tumors of the urogenital system. Our findings were summarized as follows. 1) In improved group, all of measured serum proteins returned to the normal range as the illness improved. 2) In aggravated group, changes of the serum proteins became more pronounced as the illness progressed. It was significantly noted that α_1-AG, α_1-AT, Cp and Hp increased and Pre, α_2-HS and Tf decreased in cancer of the bladder, α_1-AG increased and Pre and Tf decreased in cancer of the prostate, Hp increased and Pre and Tf decreased in the tumors of the testicle, and α_1-AG, α_1-AT and Hp increased and α_2-HS and Tf decreased in tumors of other organs.
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