Ca 拮抗剤によると思われる歯肉増殖症の 3 例

概要

論文の詳細を見る
Nifedipine, one of calcium-channel blockers, has been applied clinically to disorders such as essential hypertension, renal hypertension and angina cordis, and has been rapidly gaining popularity in Japan. This drug works on the cell membrane and obstructs the influx of calcium ions into the cell. This change depresses contractility, dilates the coronary arteries and decreases myocardial oxygen consumption. On the other hand, this drug has side effects, one of which is gingival hyperplasia. Recently, medications such as diphenylhydantoin and nifedipine have been reported to cause gingival hyperplasia. This paper presents three cases of gingival hyperplasia induced by nifedipine.
九州歯科学会の論文
1993-12-25