ビタミンB_1の拮抗物質に関する研究 : (II)Deoxythiamine B_1および類似体の乳酸菌におよぼす影響
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概要
- 論文の詳細を見る
The growth of L. fermenti 36 which requires thiamine for its growth was inhibited by deoxythiamine (DOB_1), deoxymethylthiamine (DOMB_1) and deoxyethylthiamine (DOEB_1), but not for the growth of L. arabinosus and L. casei which do not require thiamine. The inhibition of these compounds for L. fermenti was recovered competitively and specifically by thiamine and their inhibition index was 200-300 for DOB_1 and DOMB_1,about 500 for DOEB_1. These compounds had no thiamine activity. The order of decreasing antithiamine potency was : pyrithiamine > DOB_1≒DOMB_1 > DOEB_1 > thiamine sulfuric acid ester > oxythiamine.
- 日本ビタミン学会の論文
- 1961-02-25
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- はじめに
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- ビタミンB_1関連化合物の代謝 : (VI)Benzenesulfonylthiamine disulfideの代謝とその生物学的効力