放線菌の生産する抗菌性物質に關する研究(第4報) : 窒素給源と抗菌性物質生産との關係に就いて

概要

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1. Fifteen kinds of nitrogenous substance (NaNO_3,NaNO_2,NH_4NO_3,(NH_4)_2SO_4 urea, glycocoll, alanine, leucine, asparagine, tyrosine, cystine, peptone, egg-albumin, casein, and soy bean meal) were compared as nitrogen sources for the production of antibiotic substance from St. albus var. tortuosus, in the solution with glucose, galactose or lactose.2. Inorganic nitrogen compounds and urea were not suitable.3. Amoung organic nitrogenous substances, soy bean meal was most suitable for any carbon source. In the case of glucose the maximum potency of 1.000 dilution units against B. subtilis sp. was attained after 50 days. The optimum initial pH is between 6.5 and 7.5.4. It taken long to produce sufficient quantity of the antibiotic substance which is comparatively stable.
公益社団法人日本生物工学会の論文
1949-09-15