微生物の生産する抗菌性物質(第6報) : 放線菌J-4号菌の生産する抗生物質

概要

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Strain No. J-4 has the morphological and cultural characteristics resembling the s. fungicidicus G group and produces two kinds of antifungal substances (A, B) and an antibacterial substance simultaneously in a culture.One of the antifungal substances (A) belongs to the FRC group ; the other does not belong to the polyene group, for it has shown the ultraviolet absorption maxima at 212 mμ and 260 mμ.The antibacterial substance was active only against GRAM-positive species.These substances were extracted from the cultural filtrate as well as from the mycelium and obtained in crystalline form. The antifungal substance (A) decomposed at 164〜170℃, and the results of the elemental analysis indicated the following composition : C 66.79%, H 7.41%, N 5.51%, O 25.93%. The antibacterial substance melted at 175℃, and it consisted of C 66.79%, H 6.48%, N 10.33%, O 17.40%.
社団法人日本生物工学会の論文
1957-04-15