最小ノルム法を用いた心筋虚血ラットの電流源の推定

概要

論文の詳細を見る
In this study, MCGs in seven male rats were measured using a 12-channel high-resolution dc-SQUID gradiometer before and after performing coronary artery occlusion. The source imaging was estimated by minimum norm estimation (MNE). Changes in the current source distribution before and after coronary artery occlusion were clarified. As a result, in the ST segment, the current distribution significantly increased in the ischemic area. In the T wave, the direction of the current distribution clearly shifted to the left. The increased area of the estimated current distribution in the ST segment corresponded to the ischemic area. In conclusion, the large gradient potential of the left anterior region generated by the ischemic action potential produced increased currents. Our system will promote and facilitate future in vivo studies on myocardial ischemia.
社団法人日本磁気学会の論文
2001-04-15