Evaluation by Multislice Computed Tomography of Atherosclerotic Coronary Artery Plaques in Non-Culprit, Remote Coronary Arteries of Patients With Acute Coronary Syndrome
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概要
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Background Patients with acute coronary syndrome (ACS) frequently have vulnerable plaques in the remote coronary arteries, suggesting that ACS is part of the pan-coronary process. In the present study the computed tomography (CT) plaque density in non-culprit atherosclerotic coronary artery lesions was evaluated by multislice computed tomography (MSCT) in patients with ACS and non-ACS. Methods and Results MSCT was performed in 21 patients with ACS and 53 patients with non-ACS : 16 of the 21 ACS patients (76%) and 30 of the non-ACS 53 patients (57%) had non-calcified plaques in the non-culprit coronary arteries (p=0.18). CT-low-density plaques (CT density <68 Hounsfield units (HU)) were more frequent in the ACS group (13/16 patients, 81%) than in the non-ACS group (13/30 patients, 43%, p=0.03). In addition, the CT density of the non-culprit lesion was significantly lower in patients with ACS than in those with non-ACS (44.1±22.9 and 77.3±33.7HU, respectively). Conclusion Patients with ACS more frequently had CT-low-density plaques in the non-culprit, remote arteries than those with non-ACS, which suggests that ACS treatment should focus not only on stabilizing the culprit lesion but also on systemic stabilization of non-culprit lesions.
- 社団法人日本循環器学会の論文
- 2005-10-20
著者
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Sato Yuichi
Department of Imaging, Health Park Clinic Kurosawa
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SUGI Kaoru
Division of Cardiovascular Medicine, Toho University Ohashi Medical Center
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Sugi Kaoru
Division Of Cardiovascular Medicine Toho University Ohashi Medical Center
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Sugi Kaoru
Division Of Cardiology Toho University
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MOROI MASAO
Division of Cardiovascular Medicine, Toho University, Ohashi Hospital
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Kunimasa Taeko
Division Of Cardiovascular Medicine Toho University Ohashi Medical Center
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Kunimasa Taeko
Division Of Cardiovascular Medicine Ohashi Hospital Toho University School Of Medicine
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Kunimasa Taeko
Division Of Cardiovascular Medicine Toho University Ohashi Hospital
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Sato Yuichi
Department Of Imaging Health Park Clinic Kurosawa
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Moroi Masao
Division Of Cardiovascular Medicine Toho University Medical Center Ohashi Hospital
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Sato Yuichi
Department Of Cardiology Nihon University School Of Medicine
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Sato Yuichi
Department Of Applied Chemistry Faculty Of Engineering Kanagawa University
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Moroi Masao
Cardiology Division National Center For Global Health And Medicine
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Kunimasa Taeko
Division Of Cardiology Nihon University School Of Medicine
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