Noninvasive Assessment of Coronary Artery Disease by Multislice Spiral Computed Tomography Using a New Retrospectively ECG-Gated Image Reconstruction Technique : Comparison With Angiographic Results
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概要
- 論文の詳細を見る
The present study was designed to investigate the accuracy of multislice spiral computed tomography (MSCT) in detecting coronary artery disease, compared with coronary angiography (CAG), using a new retrospectively ECG-gated reconstruction method that reduced cardiac motion artifact. The study group comprised 54 consecutive patients undergoing MSCT and CAG. MSCT was performed using a SOMATOM Volume Zoom (4-detector-row, Siemens, Germany) with slice thickness 1.0mm, pitch 1.5 (table feed : 1.5mm per rotation) and gantry rotation time 500ms. Metoprolol (20-60mg) was administered orally prior to MSCT imaging. ECG-gated image reconstruction was performed with the reconstruction window (250ms) positioned immediately before atrial contraction in order to reduce the cardiac motion artifact caused by the abrupt diastolic ventricular movement occurring during the rapid filling and atrial contraction periods. Following inspection of the volume rendering images, multiplanar reconstruction images and axial images of the left main coronary artery (LMCA), left anterior descending artery (LAD), left circumflex artery (LCx) and right coronary artery (RCA) were obtained and evaluated for luminal narrowing. The results were compared with those obtained by CAG. Of 216 coronary arteries, 206 (95.4%) were assessable ; 10 arteries were excluded from the analysis because of severe calcification (n=4), stents (n=3) or insufficient contrast enhancement (n=3). The sensitivity to detect coronary stenoses [>!_]50% was 93.5% and the specificity to define luminal narrowing <50% was 97.2%. The positive predictive value and the negative predictive value were 93.5% and 97.2%, respectively. The sensitivity was still satisfactory (80.6%) even when non-assessable arteries were included in the analysis. The new retrospectively ECG-gated reconstruction method for MSCT has excellent diagnostic accuracy in detecting significant coronary artery stenoses.
- 社団法人日本循環器学会の論文
- 2003-04-20
著者
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Matsumoto Naoya
Division of Cardiology, Department of Medicine, Nihon University School of Medicine
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Sato Yuichi
Department of Imaging, Health Park Clinic Kurosawa
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Kato Masahiko
Department of Cardiovascular Medicine, Faculty of Medicine, Tottori University
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Takahashi Motoichiro
Department Of Cardiology Nihon University Surugadai Hospital
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Matsumoto Naoya
Department of Cardiology, Nihon University School of Medicine
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Katoh Masahiko
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Inoue Fumio
Division of Cardiovascular Medicine, Nihon University School of Medicine
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Inoue Fumio
Departments of Cardiology
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Kanmatsuse Katsuo
Department of Cardiology, Nihon University Surugadai Hospital
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Kato M
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Kusama Junji
Department of Cardiology, Nihon University Surugadai Hospital
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Yoshimura Akihiro
Department of Cardiology, Nihon University Surugadai Hospital
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Sato Yuichi
Department Of Imaging Health Park Clinic Kurosawa
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Kusama Junji
Department Of Cardiology Nihon University Surugadai Hospital
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Fukui Takahiro
Department of Cardiology
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Inoue Fumio
Division Of Cardiovascular Medicine Nihon University School Of Medicine
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Inoue Fumio
Department Of Hematology Dokkyo University School Of Medicine
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Kanmatsuse Katsuo
Department Of Cardiology Nihon University Hospital
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KANMATSUSE Katsuo
Surugadai Nihon University Hospital
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Furuhashi Satoru
Department Of Radiology Nihon University School Of Medicine
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Imazeki Takako
Department of Cardiology, Nihon University Surugadai Hospital
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Matsumoto Naoya
Department Of Anatomy And Neurobiology Kyoto University Graduate School Of Medicine
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Imazeki Takako
Departments Of Cardiology Nihon University Surugadai Hospital
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Horie Toshiyuki
Department of Cardiology, Nihon University Surugadai Hospital
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Kato Masahiko
Department Of Allergy And Immunology Gunma Children's Medical Center
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Yoshimura Akihiro
Department Of Cardiology Nihon University School Of Medicine
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Miki Takaaki
Division Of Cardiology Department Of Medicine Nihon University School Of Medicine
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Horie Toshiyuki
Departments Of Cardiology Nihon University Surugadai Hospital
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Sato Yoshiyuki
Department Of Cardiology Nihon Univeristy School Of Medicine
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Kanmatsuse Katsuo
Department Of Cardiology
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Sato Yuichi
Department Of Applied Tumor Pathology Kitasato University Graduate School Of Medical Sciences
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Yoshimura Akihiko
Department Of Cardiology Nihon University School Of Medicine
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Kusama Junji
Departments Of Cardiology Nihon University Surugadai Hospital
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Sato Yuichi
Department Of Applied Chemistry Faculty Of Engineering Kanagawa University
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Furuhashi Satoru
Radiology Nihon University School Of Medicine
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Matumoto Naoya
Department Of Cardiology Nihon University School Of Medicine
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Inoue Fumio
Department Of Cardiology Nihon University School Of Medicine
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