Resistance to Proteolysis of Antibody Ligands Modified with Polyethylene Glycol
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概要
- 論文の詳細を見る
Antibody ligands coupled to Sepharose 4B and Formyl Cellulofine were modified with polyethylene glycol(PEG)activated with N-hydrozysuccinimide ester. The decrease in the antigen binding activity by the modification was much less than that with cyanuric chloride-activated PEG. Since the resistance to proteolytic digestion of the immunoadsorbents was improved by the modification, suitably modified immunoadsorbents showed higher adsorption capacities than those of unmodified ones after digestion by pronase.
- 公益社団法人日本生物工学会の論文
- 1991-02-25
著者
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YAMANAKA KATSUHIRO
Department of Bioscience and Biotechnology, Faculty of Engineering, Okayama University
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Katoh S
Graduate School Of Science And Technology Kobe University
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Katoh S
Department Of Chemical Science And Engineering Graduate School Of Engineering Kobe University:depart
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KATOH SHIGEO
Chemical Engineering Department, Kyoto University
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Sada E
Kyoto Univ. Kyoto
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Sada Eizo
Chemical Engineering Department Kyoto University
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Yamanaka Katsuhiro
Department Of Bioscience And Biotechnology Faculty Of Engineering Okayama University
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YAMANAKA KUNIKO
Chemical Engineering Department, Kyoto University
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ITAKURA YASUSHI
Chemical Engineering Department, Kyoto University
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Itakura Yasushi
Chemical Engineering Department Kyoto University
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Katoh Shigeo
Chemical Engineering Department Kyoto University
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