Properties of a High-Torularhodin-Producing Mutant of Rhodotorula glutinis Cultivated under Oxidative Stress

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概要

• 論文の詳細を見る

• To characterize the properties of torularhodin, which is one of the carotenoid pigments produced by the yeast Rhodotorula sp., a mutant which produces large amounts of torularhodin was constructed and its tolerance against oxidative stress was investigated. The mutant we obtained was capable of producing large amounts of torularhodin in response to irradiation with blue light. The mutant, incubated under irradiation with white light that resulted in an increased production of torularhodin, exhibited resistance to growth inhibition induced by the addition of methylene blue as the generator of singlet oxygen. Leakage of lactate dehydrogenase to the growth medium from the mutant was not increased as compared to that from a parent strain and a high-β-carotene-producing mutant. These results suggest that an increase in the production of torularhodin reduces the susceptibility to injury induced by an active oxygen species.

• 社団法人日本生物工学会の論文
• 2000-02-25

著者

• MIKI Wataru

  Institute for Fundamental Research, Suntory Limited

• MIKI WATARU

  Suntory Co., Ltd

• KOMEMUSHI SADAO

  School of Agriculture, Kinki University

• KOMEMUSHI SADAO

  Department of Agricultural Chemistry, School of Agriculture, Kinki University

• Miki Wataru

  Fuji Chemical Ind. Co. Ltd.

• Miki W

  Marine Biotechnol. Inst. (mbi) Shizuoka Jpn

• Miki Wataru

  Institute For Fundamental Research Suntory Limited

• Nakanishi Taisuke

  Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University

• SAKAKI HIDEYUKI

  Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University

• NAKANISHI TATSUYA

  Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University

• SATONAKA KEN-YA

  Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University

• FUJITA TOKIO

  Department of Agricultural Chemistry, Faculty of Agriculture, Kinki University

• Fujita Tokio

  Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University

• Satonaka Ken-ya

  Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University

• Sakaki Hideyuki

  Kobe Creative Center Senju Pharmaceutical Co. Ltd

• Komemushi S

  School Of Agriculture Kinki University

• Komemushi Sadao

  Department Of Agricultural Chemistry Faculty Of Agriculture Kinki University

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