Synthesis of Gibbilimbols A-D, Cytotoxic and Antibacterial Alkenylphenols Isolated from Piper gibbilimbum
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概要
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Gibbilimbols A [(E)-4-(4-decenyl)phenol, 1], B [(E)-4-(3-decenyl)phenol, 2], C [(E)-4-(4-octenyl)phenol, 3] and D [(E)-4-(3-octenyl)phenol, 4] were synthesized by coupling the phenolic parts with the alkyne parts and then reducing the triple bond of the resulting alkynylphenols. These alkenylphenols (1-4) are the cytotoxic and antibacterial constituents of the leaves of a medicinal plant (Piper gibbilimbum) that is used as a traditional medicine in Papua New Guinea.
- 2001-03-23
著者
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Abe Yumi
Department Of Mathematics And Science Education Graduate School Of Science
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Abe Yumi
Department Of Applied Chemistry Faculty Of Engineering Oita University
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Takikawa Hirosato
Department Of Agrobioscience Graduate School Of Agricultural Science Kobe University
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Mori Kenji
Department Of Biochemistry National Cardiovascular Center Research Institute
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Mori Kenji
Department Of Agricultural Chemistry College Of Science And Technology The University Of Tokyo
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Mori Kenji
Department Of Mathematics And Science Education Graduate School Of Science:department Of Chemistry F
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