Synthesis of the Racemate of the Stereoisomer at C-6a of BE-40644,a Bioactive Metabolite of Actinoplanes sp. with a Sesquiterpene-substituted p-Benzoquinone Structure

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概要

• 論文の詳細を見る

• BE-40644 is a tetracyclic metabolite of Actinoplanes sp. A 40644 possessing a sesquiterpene-substituted p-benzoquinone structure with cis-fused B/C ring stereochemistry that inhibits the human thioredoxin system as the well as the growth of several cancer cell lines. Its B/C trans-fused stereoisomer at C-6a was synthesized as a racemate starting from geranylacetone and 3,5-dihydroxybenzoic acid.

• 社団法人日本農芸化学会の論文
• 2001-01-23

著者

• Mori Kenji

  Department Of Agricultural Chemistry College Of Science And Technology The University Of Tokyo

• TSUJIMORI Hisayuki

  Department of Chemistry, Faculty of Science, Science University of Tokyo

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