Recognition of Ribose Moiety by Adenosine (Phosphate) Deaminase from Squid Liver

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概要

• 論文の詳細を見る

• An adenosine (phosphate) deaminase from the squid liver had much lower activity for 5'-deoxyadenosine than that for adenosine, 2'-, or 3'-deoxyadenosine. 3'-IMP and inosine as well as purine riboside and adenine competitively inhibited the deamination of adenosine 3'-phenylphosphonate by the enzyme, but 5'-AMP and 5'-IMP did not. The enzyme deaminated the 5'-hydroxyl terminal adenosine residue in dinucleotides and trinucleotide, but not the 3'-hydroxyl terminal one in dinucleotides. The 5'-hydroxyl group of the ribose moiety was necessary for the substrate binding and catalytic activity of the squid enzyme. These results indicated that the recognition of ribose moiety in the substrate by the squid enzyme might be intermediate between those by adenosine deaminase and adenosine (phosphate) deaminase from microorganisms.

• 社団法人日本農芸化学会の論文
• 1995-11-23

著者

• UCHIDA Hiroyuki

  Department of Earth and Space Science, Osaka University

• NOMURA Akihiko

  Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University

• CHEN Yi-Xin

  Department of Applied Chemistry and Biotechnology, Faculty of Engineering, Fukui University

• Chen Y‐x

  Fukui Univ. Fukui Jpn

• Chen Yi-xin

  Department Of Applied Chemistry And Biotechnology Faculty Of Enginnering Fukui University

• Chen Y‐x

  Zhejiang Institute Of Modern Physics Zhejiong University

• CHEN Yi-xin

  Zhejiang Institute of Modern Physics, Zhejiong University

• Narita Yuki

  Department of Applied Chemistry and Biotechnology, Faculty of Enginnering, Fukui University

• Masuda Akihiko

  Department of Applied Chemistry and Biotechnology, Faculty of Enginnering, Fukui University

• Uchida Hiroyuki

  Department Of Applied Chemistry And Biotechnology Graduate School Of Engineering University Of Fukui

• Uchida H

  Department Of Physics Kyushu University

• Narita Yuki

  Department Of Applied Chemistry And Biotechnology Faculty Of Enginnering Fukui University

• Chen Yi-xin

  Department Of Applied Chemistry And Biotechnology Faculty Of Engineering Fukui University

• Chen Yi-xin

  Zhejiang Institute Of Modern Physics Zhejiang University

• Masuda A

  Kyoto Univ. Kyoto Jpn

• Nomura A

  Faculty Of Education Yamaguchi University

• Uchida H

  Fukui Univ. Fukui Jpn

• Nomura Akihiko

  Department Of Applied Chemistry And Biotechnology Faculty Of Enginerring Fukui University

• Uchida Hiroyuki

  Department Of Applied Chemistry And Biotechnology Faculty Of Engineering University Of Fukui

• Uchida Hiroyuki

  Department Of Applied Chemistry And Biotechnology Faculty Of Engineering Fukui University

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