Angiotensin I-Converting Enzyme Inhibitory Activity and Insulin Secretion Stimulative Activity of Fermented Fish Sauce
スポンサーリンク
概要
- 論文の詳細を見る
Angiotensin I-converting enzyme (ACE) inhibitory peptides, Ala-Pro, Lys-Pro, and Arg-Pro, were isolated from fermented fish sauce. Five other proline-containing dipeptides having weak ACE inhibitory activity were also isolated from the fermented fish sauce. Orally administered Lys-Pro showed a tendency to lower the blood pressure of spontaneously hypertensive rats. As fermented anchovy sauce also stimulated insulin secretion by cultured RINm5F insulinoma cells, the sauce may be useful as a source of biologically active substances.
- 社団法人日本生物工学会の論文
- 2003-11-25
著者
-
Ichimura Toshiaki
Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science
-
MARUYAMA Susumu
Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science
-
HU Jianen
Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science
-
AITA DUONG
Niigata Research Laboratory, Mitsubishi Gas Chemical Company, Inc.
-
Maruyama Susumu
Fermentation Research Institute
-
Maruyama Susumu
Institute For Biological Resources And Functions National Institute Of Advanced Industrial Science A
-
Maruyama Susumu
National Institute Of Bioscience And Human Technology Agency Of Industrial Science And Technology
-
Aita Duong
Niigata Research Laboratory Mitsubishi Gas Chemical Company Inc.
-
Ichimura Toshiaki
Institute For Biological Resources And Functions National Institute Of Advanced Industrial Science A
-
Ichimura T
Institute For Biological Resources And Functions National Institute Of Advanced Industrial Science A
-
Hu Jianen
Institute For Biological Resources And Functions National Institute Of Advanced Industrial Science A
-
Atia Duong
Niigata Research Laboratory, Mitsubishi Gas Chemical Company, Inc.
関連論文
- Antihypertensive Effect of Enzymatic Hydrolysate of Collagen and Gly-Pro in Spontaneously Hypertensive Rats
- Antihypertensive Effect of an Extract of Passiflora edulis Rind in Spontaneously Hypertensive Rats
- Luteolin Inhibits Endothelin-1 Secretion in Cultured Endothelial Cells
- A Synthetic Polymer, Poly(2-methacryloyloxyethyl phosphorylcholine-co-n-stearyl methacrylate), Stimulated Insulin Release from RINm5F Insulinoma Cells
- Angiotensin I-Converting Enzyme Inhibitory Activity and Insulin Secretion Stimulative Activity of Fermented Fish Sauce
- Hypotensive Activity of Enzymatic α-Zein Hydrolysate(Biological Chemistry)
- Structures and Activity of Angiotensin-converting Enzyme Inhibitors in an α-Zein Hydrolysate(Biological Chemistry)
- Angiotensin I-Converting Enzyme Inhibitory Activities of Synthetic Peptides Related to the Tandem Repeated Sequence of a Maize Endosperm Protein(Food & Nutrition)
- Aminopeptidase P, Capable of Hydrolyzing Oligoproline, from Bovine Brain
- Inhibition of HIV-1 Protease by Water-Soluble Lignin-Like Substance from an Edible Mushroom, Fuscoporia obliqua
- Antihypertensive Effect of Enzymatic Hydrolysate of Collagen and Gly-Pro in Spontaneously Hypertensive Rats
- In Vitro and in Vivo Anti-platelet Effects of Enzymatic Hydrolysates of Collagen and Collagen-related Peptides
- Prolylendopeptidase Inhibitory Activity of a Glial Fibrillary Acidic Protein Fragment and Other Proline-rich Peptides
- Prolyl Endopeptidase Inhibitory Activity of Peptides in the Repeated Sequence of Various Proline-Rich Proteins
- Angiotensin I-Converting Enzyme Inhibitors Derived from Ficus carica(Biological Chemistry)
- HIV-1 Protease Inhibition and Anti-HIV Effect of Natural and Synthetic Water-soluble Lignin-like Substances
- Purification of angiotensin I-converting enzyme inhibitors in pelagic thresher Alopias pelagicus muscle hydrolysate and viscera extracts
- Angiotensin I-Converting Enzyme Inhibitor Derived from an Enzymatic Hydrolysate of Casein. II. Isolation and Bradykinin-potentiating Activity on the Uterus and the Ileum of Rats
- Studies on the Active Site and Antihypertensive Activity of Angiotensin I-Converting Enzyme Inhibitors Derived from Casein
- Angiotensin I-Converting Enzyme Inhibitory Activity of the C-Terminal Hexapeptide of αs1-Casein
- A Peptide Inhibitor of Angiotensin I Converting Enzyme in the Tryptic Hydrolysate of Casein