SERUM LIPID AND LIPOPROTEIN PROFILES IN PATIENTS WITH XANTHOMAS : A Correlative Study on Xanthoma and Atherosclerosis (I)
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概要
- 論文の詳細を見る
In an attempt to correlate xanthomas with atherosclerosis, the characteristics of serum lipid and lipoprotein profiles are explored in xanthoma patients. Xanthomas are classified into 5 subtypes: xanthelasma, planar xanthoma, papulo-eruptive xanthoma, tuberous xanthoma and tendon xanthoma. The clinical characteristics of xanthoma patients are summarized in the following, 1) Xanthelasma in 2 different types: one normolipemic and the other hyperlipidemic; of 30 xanthelasma patients, 5 were normolipemic. one of them had low HDL-cholesterol. 2) Tuberous and tendon xanthomas were all hypercholesterolemic, with serum cholesterol above 300 mg/dl and LDL-cholesterol above 255 mg/dl, while HDL-cholesterol was within normal range. 3) The xanthoma patients were generally not obese. 4) Their laboratory findings often showed such abnormalities as elevated levels in serum fibrinogen, LDH, CPK and uric acid. The resemblance of the clinical characteristics between xanthomas and atherosclerotic vascular disease, e.g., myocardial infarction, was striking. If the causation of their common tissue alterations by lipid accumulation is pathologically and biochemically defined, the correlation between those 2 kinds of disease can be. established.
- 社団法人日本循環器学会の論文
- 1981-11-20
著者
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Tsushima Motoo
Department of Internal Medicine, Keio University School of Medicine
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Hata Yoshiya
Department Of Geriatrics Kyorin University Medical School
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Shigematsu Hiroshi
Department Of Medicine Keio University School Of Medicine
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HIROSE Nobuyoshi
Department of Geriatric Medicine, Keio University Medical School
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Tsushima Motoo
Department Of Medicine Keio University School Of Medicine
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OIKAWA TAKAMITSU
Department of Medicine, Keio University School of Medicine
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YAMAMOTO MINORU
Department of Medicine, Keio University School of Medicine
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YAMAUCHI YOSHIO
Department of Medicine, Keio University School of Medicine
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Tsushima Motoo
Department Of Atherosclerosis And Metabolism
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Yamamoto Minoru
Department Of Gastroenterological Surgery Nagoya City University
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Yamauchi Yoshio
Department Of Medicine Keio University School Of Medicine
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Hirose Nobuyoshi
Department Of Medicine Keio University School Of Medicine
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Hirose Nobuyoshi
Department Of Geriatric Medicine Keio University Medical School
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Oikawa Takamitsu
Department Of Medicine Keio University School Of Medicine
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Hata Yoshiya
Department Of Medicine Keio University School Of Medicine
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Hata Yoshiya
Dept. Of Med. Keio Univ.
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Yamamoto Minoru
Department Of Medicine Keio University School Of Medicine
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Yamamoto Minoru
Department Of Ecosystem Engineering The University Of Tokushima
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Yamauchi Yoshio
Department Of Biochemistry Ii Nagoya University Graduate School Of Medicine
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Shigematsu Hiroshi
Dept. Of Intern. Med. School Of Med. Keio Univ.
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Shigematsu Hiroshi
Department of Electrical and Electronic Engineering, Yamaguchi University,
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