SIMILARITY OF LIPID INCLUSIONS IN EXPERIMENTAL ATHEROSCLEROSIS OF RABBITS TO THOSE OF HUMANS (HISTO- AND CYTOCHEMISTRY OF LIPIDS)

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概要

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• A comparative study was made on lipid inclusions of human and rabbits. Atherosclerotic lesions were produced in rabbits fed 0.67% cholesterol for seven months. The loci of the inclusions produced in tissue, three-dimensional configuration, crystallographic characteristics, physical properties and chemical compositions were compared, and found to be similar and even identical between man and rabbit. The lipid inclusions were thus presumed to be formed in arterial tissues by a cellular metabolism common to man and rabbit, and shaped by a physico-chemical effect independent of difference in species. Hence, rabbits are found usable as a model for the study of lipid inclusions in experimentally induced atherosclerosis.

• 日本組織細胞化学会の論文

著者

• Tsushima Motoo

  Department of Internal Medicine, Keio University School of Medicine

• Hata Yoshiya

  Department Of Geriatrics Kyorin University Medical School

• Shigematsu Hiroshi

  Department Of Medicine Keio University School Of Medicine

• Aihara Kazuo

  Keio University School Of Medicine Tokyo Dental College Ichikawa Hospital

• Aihara Kazuo

  Department Of Physiology Showa University School Of Medicine

• Tsushima Motoo

  Department Of Medicine Keio University School Of Medicine

• MIYAZAKI KAZUE

  Department of Medicine, Keio University School of Medicine

• Miyazaki Kazue

  Department Of Medicine Keio University School Of Medicine

• Tsushima Motoo

  Department Of Atherosclerosis And Metabolism

• Hata Yoshiya

  Department Of Medicine Keio University School Of Medicine

• Hata Yoshiya

  Dept. Of Med. Keio Univ.

• Shigematsu Hiroshi

  Dept. Of Intern. Med. School Of Med. Keio Univ.

• Miyazaki Kazue

  Department of Chemistry, Faculty of Science, Nara Women's University

• Shigematsu Hiroshi

  Department of Electrical and Electronic Engineering, Yamaguchi University,

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