Prevalence, Awareness and Treatment of Cardiovascular Risk Factors in Patients at High Risk of Atherothrombosis in Japan : Results From Domestic Baseline Data of the REduction of Atherotherombosis for Continued Health(REACH) Registry

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概要

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• Background The REduction of Atherothrombosis for Continued Health(REACH) Registry is an international observational study of patients with, or at risk of, atherothrombotic disease. Japanese patients were analyzed to clarify national prevalence and treatment. Methods and Results Almost 68,000 outpatients were recruited worldwide with 5,193 in Japan. Among the Japanese patients, 83.7% had established vascular disease (symptomatic) and 16.3% had risk factors only (asymptomatic). Of the symptomatic patients, 14.0% had atherothrombotic lesions in more than 1 vascular bed, with 0.8% having lesions in 3 areas: brain, heart, and peripheral arteries. The prevalence of additional atherothrombotic risk factors among symptomatic patients was independent of the vascular lesion. Obesity was recorded in 10.6% and 42.1% of patients according to the National Cholesterol Education Program and Japanese guidelines, respectively. Pharmacologic intervention for risk factors was inadequate: only 37.7% of diabetic patients received antidiabetic medication, 79.6% of hypertensive patients used antihypertensives, and 74.0% received antiplatelet agents. The use of statins (44.1%) and aspirin (54.7%) was less common than seen in REACH globally. Conclusions Japanese patients enrolled in REACH share many similarities with the global population, but with some important differences. Long-term follow-up will determine the impact of these factors on the development of atherothrombotic events.

• 社団法人日本循環器学会の論文
• 2007-06-20

著者

• NAGAI Ryozo

  Department of Cardiovascular Medicine, University of Tokyo

• UMEMURA Satoshi

  Yokohama City University

• YAMADA Nobuhiro

  Department of Internal Medicine, University of Tsukuba

• SHIMADA Kazuyuki

  Department of Medicine, Jichi Medical University

• Matsuzaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Yajima Toshimi

  The Cardiovascular Institute Department Of Medicine Keio University School Of Medicine

• Umemura Satoshi

  日本大学 医学部内科学系腎臓高血圧内分泌内科

• Matsumoto Masayasu

  Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedi

• Origasa Hideki

  Department Of Biostatistics University Of Toyama

• Yamada Nobuhiro

  The Research Committee For Primary Hyperlipidemia Research On Measures For Intractable Diseases By T

• Yamazaki Tsutomu

  Department of Clinical Epidemiology & Systems, The University of Tokyo

• Uchiyama Shinichiro

  Department Of Neurology Tokyo Women's Medical University

• Sugimoto Ken

  東北大学 臨床薬学

• Matsubara Mitsunobu

  Department Of Medicine And Clinical Science Yamaguchi University Graduate School Of Medicine

• Miyahara Mitsuo

  The Second Department Of Internal Medicine Sapporo Medical College

• Shigematsu Hiroshi

  Department Of Medicine Keio University School Of Medicine

• Shigematsu Hiroshi

  Department Of Vascular Surgery Tokyo Medical University

• GOTO Shinya

  Department of Internal Medicine, Tokai University

• Orikasa Hideki

  Division Of Biostatistics And Clinical Epidemiology University Of Toyama University Of Toyama School

• Yamada Nobuhiro

  Department Of Internal Medicine University Of Tsukuba Institute Of Clinical Medicine

• Yamada Nobuhiro

  筑波大学 人間総合科学研究科代謝内分泌学

• Shimamoto Kazuaki

  帝京大学 医学部内科

• Ikeda Yasuo

  Department Of Internal Medicine Keio University

• Nagai Ryouzou

  Departmnet Of Cardiology University Of Tokyo

• Origasa Hideki

  Department Of Biostatistics Faculty Of Medicine Toyama Medical And Pharmaceutical University

• Yamazaki Tsutomu

  Department Of Clinical Epidemiology & Systems Graduate School Of Medicine The University Of Toky

• Bhatt Deepak

  Department of Cardiovascular Medicine, Cleveland Clinic Foundation

• Steg P.

  Departement de Cardiologie, Hopital Bichat-Claude Bernard

• Uchiyama Shinichiro

  Department Of Neurology Neurological Insitute Tokyo Women's Medical University

• Matsuzaki Masunori

  Department Of Cardiovascular Medicine Yamaguchi University Graduate School Of Medicine

• Yamada Nobuhiro

  Department Of Internal Medicine (endocrinology And Metabolism) Graduate School Of Comprehensive Huma

• Bhatt Deepak

  Department Of Cardiovascular Medicine Cleveland Clinic Foundation

• Goto Shinya

  Department Of Internal Medicine Tokai University

• Yamada Nobuhiro

  Department Of Chemistry And Chemical Engineering Yamagata University

• Ikeda Yasuo

  Department Of Earth Science Hokkaido University Of Education At Kushiro

• Steg P.

  Departement De Cardiologie Hopital Bichat-claude Bernard

• Matsuzaki Masunori

  Division Of Cardiology Department Of Medicine And Clinical Science Graduate School Of Medicine Yamag

• Umemura S

  Department Of Second Internal Medicine Yokohama City University School Of Medicine

• Miyahara Mitsuo

  Dept. Of Intern. Med. (section 2) Sapporo Med. Coll.

• Shimada Kazuyuki

  Department Of Anatomy School Of Medicine Showa University

• Mori Masaki

  Division Of Gene Therapy Science Osaka University

• Yamaguchi Tetsu

  Department Of Internal Medicine (metabolism And Endocrinology) Graduate School Of Comprehensive Huma

• Yamazaki Tsutomu

  Department Of Applied Chemistry Tokyo University Of Agriculture And Technology

• Goto Shinya

  Department Of Cardiology Tokai University School Of Medicine

• Nagai Ryozo

  Department Of Cardiology Kitano Hospital Medical Research Institute

• Yamada Nobuhiro

  Department Of Internal Medicine (endocrinology And Metabolism) Graduate School Of Comprehensive Huma

• Yamada Nobuhiro

  Department Of Internal Medicine (endocrinology And Metabolism) Graduate School Of Comprehensive Huma

• Miyahara Mitsuo

  Second Department Of Internal Medicine Sapporo Medical College

• Yamada Nobuhiro

  Department Of Internal Medicine (endocrinology And Metabolism) Graduate School Of Comprehensive Huma

• Yamazaki Tsutomu

  Department Of Applied Chemistry Graduate School Of Engineering Tokyo University Of Agriculture And T

• Nagai Ryozo

  Department Cardiovascular Medicine The University Of Tokyo Hospital

• Miyahara Mitsuo

  2nd Div. Dept. Of Intern. Med. Sapporo Med. Coll.

• Ikeda Yasuo

  Department Of Life Science And Medical Bioscience Waseda University School Of Advance Science And En

• Goto Shinya

  Department Of Cardiology Tokai University

• Matsumoto Masayasu

  Department Of Clinical Neuroscience And Therapeutics Graduate School Of Biomedical Science Hiroshima University

• SHIGEMATSU Hiroshi

  Department of Vascular Surgery, Tokyo Medical University

• Uchiyama Shinichiro

  Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University

• Shigematsu Hiroshi

  Department of Electrical and Electronic Engineering, Yamaguchi University,

• Matsumoto Masayasu

  Department of Clinical Neuroscience and Therapeutics Division of Integrated Medical Science, Graduate School of Biomedical Sciences, Hiroshima University

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