APPLICATION OF FRIEDEWALD'S LDL-CHOLESTEROL ESTIMATION FORMULA TO SERUM LIPIDS IN THE JAPANESE POPULATION
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概要
- 論文の詳細を見る
When direct measurement of serum low density lipoprotein cholesterol (LDL-c) is not available, it can be estimated from total cholesterol (TC), triglycerides (TG) and high density lipoprotein cholesterol (HDL-c) by using the formula proposed by Friedewald : LDL-c = TC- [HDL-c + TG/k], k =5 This formula assumes the triglyceride/cholesterol ratio in VLDL to be 5:1. However, it is changeable with serum triglyceride levels, and averaged as 4 among Japanese with triglycerides less than 400 mg/dl. The formula provides a better fit for Japanese people, when k=4, rather than original k=5. In addition, a better estimation is gained, if k is rotated according to the triglyceride levels of individual subjects ; i.e. 3 for those with triglycerides less than 150 mg/dl, 4 for those with triglycerides from 150 to 299 mg/dl, 5 for those with triglycerides from 300 to 400 mg/dl. The percent error of estimation is less than 5% when k=4, and about 1% when variable k is employed for populations of about 1,000 subjects in number.
- 社団法人日本循環器学会の論文
- 1986-12-20
著者
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Hata Yoshiya
Department Of Geriatrics Kyorin University Medical School
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Nakajima Kumiko
Department Of Chemistry College Of Humanities And Sciences Nihon University
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Nakajima Kumiko
Department Of Medicine Keio University School Of Medicine
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