Factors Affecting Molecular Weight Conversion of Renin : IX Conference on the Pathogenesis of Hypertension
スポンサーリンク
概要
- 論文の詳細を見る
Our recent findings on molecular weight conversion in the case of renin are summarized and reviewed herein. The molecular weight of renin extracted from isolated renin granules from dogs and rats is approximately 40,000. This renin reacts with a constituent of kidney extract to form a high molecular weight renin of approximately 60,000. This constituent was termed a renin binding substance. This substance is probably contained in the cytosol of kidney cortex, and its characteristics are (1) heat instability, (2) non-dialyzability, (3) loss of binding ability by acidification at pH 3.0 and (4) apparent molecular weight is over 47,000. The binding reaction is mediated in two different ways; thiol oxidation with sodium tetrathionate and exposure of the reaction mixture at 0℃ for several days without thiol oxidation.
- 社団法人日本循環器学会の論文
- 1980-06-20
著者
-
IKEMOTO FUMIHIKO
Department of Pharmacology, Osaka City University Medical School
-
TAKAORI KAZUO
First Department of Internal Medicine, Osaka City University Medical School
-
Takaori Kazuo
First Department Of Internal Medicine Osaka City University Medical School
-
Yamamoto Kenjiro
The Department Of Pharmacology Osaka City University Medical School
-
Kawamura Minoru
The Department Of Pharmacology Osaka City University Medical School
-
Ikemoto Fumihiko
Department Of Pharmacology Osaka City University Medical School
-
IKEMOTO FUMIHIKO
the Department of Pharmacology, Osaka City University Medical School
-
TAKAORI KAZUO
the Department of Pharmacology, Osaka City University Medical School
-
Ikemoto Fumihiko
The Department Of Pharmacology Osaka City University Medical School
-
Yamamoto Kenjiro
Dept. Of Pharm. Osaka City Univ. Medical School
関連論文
- EFFECTS OF PROSTAGLANDIN I_2 AND E_2 ON RENAL HEMODYNAMICS AND FUNCTION AND RENIN RELEASE
- Effects of Calcium Ionophore, A23187, on Prostaglandin E_2 and Renin Release in Dogs : IX Conference on the Pathogenesis of Hypertension
- EFFECTS OF OUABAIN ON RENIN SECRETION : Hypertension I : Ist Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 1979
- -EFFECT OF CALCIUM AND CALCIUM ANTAGONISTS ON RENAL FUNCTIONS AND RENIN RELEASE IN DOGS : IInd Auditorium
- Control of Renin Secretion : SYMPOSIUM ON PATHOGENESIS OF ESSENTIAL HYPERTENSION
- Effect of Ca on Renin Release in Vitro and in Vivo (3 Conference of Pathogenesis of Hypertension)
- Renin-Angiotensin System in Genetically Hypertensive Mice : THE 13TH CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- Subcellular Localization of Exogenously Administered Renin in Mouse Kidney : The 12th Conference on the Pathogenesis of Hypertension
- Sandwich Radioimmunoassay of Human Plasma Renin Using Two Monoclonal Antibodies : THE 17th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- Relationship between Molecular Weight Conversion and Renin Activity in Dog Renal Renin : VIII CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- -239-THE SECRETION OF ACTIVE AND INACTIVE FORMS OF RENIN IN THE DOG : Renin,Angiotensin : PROCEEDINGS OF THE 42nd ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- EFFECTS OF PROSTAGLANDIN A_2 AND E_2 ON RENAL FUNCTION AND RENIN RELEASE
- RENAL CORTEX BLOOD FLOW RESPONSES TO ADRENERGIC DRUGS : PROCEEDINGS OF THE 38TH ANNUAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- EFFECTS OF RENAL VENOUS PRESSURE ELEVATION ON RENAL HEMODYNAMICS, URINE FORMATION AND RENIN RELEASE
- CONTROL OF RENIN SECRETION IN THE ANESTHETIZED DOG (3) EFFECTS OF HYPERTONIC MANNITOL INFUSION
- Control of Renin Secretion in the Anesthetized Dog 2) Relationship between Renin Secretion, Plasma Sodium Concentration and GFR in the Perfused Kidney
- Adenine nucleotides and renal function : Special reference with intrarenal distribution of blood flow.
- Effects of Cyclic AMP and Dibutyryl Cyclic AMP on Renin Release in Vivo and in Vitro
- The Use of Labeled Microsphere to Measure Intrarenal Distribution of Blood Flow : THE 31ST KINKI REGIONAL MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Perfusion Method for the Dog Kidney with an Artificial Heart-Lung Apparatus
- 78. Studies of Renin Release: Release of Renin from Dog Kidney Cortex Slices
- Control of Renin Secretion in the Anesthetized Dog : 1) Relationship between Renin Secretion and Plasma Sodium Concentration in the Peritoneal Dialyzed Dog
- Renal Vascular Response to Ganglionic Stimulants in the Dog
- RELATIONSHIP BETWEEN INTRARENALDISTRIBUTION OF BLOOD FLOW AND RENIN SECRETION DURING URETERALOCCLUSION
- EFFECT OF D-3-ACETOXY-2,3-DIHYDRO-5-2-(DIMETHYLAMINO) ETYL-2-(P-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4 (5H)-ONE-HYDROCHLORIDE (CRD) ON RENAL FUNCTION IN THE DOG
- Renin Inhibition by Synthetic Phosphatidyl and Phosphorylethanolamines
- Relationship between Renin Secretion and Renal Autoregulation in the dogs
- STUDY OF HYPERTENSION : INTRAVENOUS AND INTRAVENTRICULAR ADMINISTRATION EFFECT OF ANGIOTENSIN II ON CARDIO-VASCULAR SYSTEM
- Diuretic Action of Isoproterenol in the Dog
- Factors Affecting Molecular Weight Conversion of Renin : IX Conference on the Pathogenesis of Hypertension
- Effect of Angiotensin II on Renal Hemodynamics and Urinary Excretion of Sodium and Potassium in the Rat
- Vascular Responsiveness to Angiotensin II and Phenylephrine, the Tubular Function and the Prostaglandin, Renin-Angiotensin System in a Patient with Bartters Syndrome
- Angiotensin converting enzyme inhibitory substance exists in the rat heart
- High molecular weight renin in the plasma and kidney of SHRSP