Cardiac Sympathetic Dysfunction in an Athlete's Heart Detected by ^<123>I-Metaiodobenzylguanidine Scintigraphy
スポンサーリンク
概要
- 論文の詳細を見る
The athlete's heart is commonly characterized by an increase in left ventricular mass because of an increase in the left ventricular diastolic cavity dimensions or wall thickness or both. Endurance exercise also induces numerous cardiovascular adaptations, including increased vagal tone. However, the sympathetic function has not yet been precisely elucidated, so the present study evaluated cardiac sympathetic nerve function from metaiodobenzylguanidine (MIBG) images obtained 15 and 180min after the injection of ^<123>I-MIBG at a dose of 111 MBq. The ratio of heart/mediastinum count (H/M) and the washout rates of ^<123>I-MIBG (WR) were calculated in 25 consecutive patients who were athletes (aged 52±13 years) and 23 normal subjects. There was a significant difference in the H/M between the athletic and normal hearts (2.3±0.3 vs 2.6±0.3, p<0.01, Scheffe's test). An increased WR was observed in the athletes group when compared with the normal group (34±4 vs 28±3, p<0.01), and there was a significant correlation between WR and the left ventricular mass index (r=0.578, p<0.01). Prolonged exercise training may alter cardiac sympathetic nerve function, which can be detected by MIBG imaging.
- 社団法人日本循環器学会の論文
- 2001-04-20
著者
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Kinoshita Masahiko
First Department of Internal Medicine, Shiga University of Medical Science
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Matsuo Shinro
滋賀医科大学 内科学第一
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Matsuo Shinro
滋賀医科大学 呼吸循環器内科
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Nakamura Yasuyuki
First Department of Internal Medicine, Shiga University of Medical Science
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MATSUO Shinro
First Department of internal Medicine, Shiga University of Medical Science
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MATSUI Toshiki
First Department of internal Medicine, Shiga University of Medical Science
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Kusukawa Junya
First Department of Internal Medicine, Shiga University of Medical Science
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Yoshida Shintaro
First Department Of Internal Medicine Shiga University Of Medical Science
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Takahashi Masayuki
First Department of Internal Medicine,Shiga University of Medical science
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Nakamura Yasuyuki
Heart Rhythm Center Department Of Cardiovascular Medicine Shiga University Of Medical Science
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Kusukawa Junya
First Department Of Internal Medicine Shiga University Of Medical Science
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Kinoshita Masahiko
First Department Of Internal Medicine
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Horie Hajime
First Department Of Internal Medicine Shiga University Of Medical Science
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Hamamoto Hajime
First Department of Internal Medicine, Shiga University of Medical Science
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Matsui Toshiki
First Department Of Internal Medicine Shiga University Of Medical Science
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Hamamoto Hajime
First Department Of Internal Medicine Shiga University Of Medical Science
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Takahashi Masayuki
First Department Of Internal Medicine Shiga University Of Medical Science
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Nakamura Yasuyuki
First Department Of Internal Medicine Shiga University Of Medical Science
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