Incidence of Ischemic Strokes in Hypertrophic Cardiomyopathy is Markedly Increased if Complicated by Atrial Fibrillation
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概要
- 論文の詳細を見る
The clinical outcome and the incidence of ischemic strokes in patients with hypertrophic cardiomyopathy (HCM) with and without atrial fibrillation (AF) were examined. Eighty-three patients with HCM, complicated by AF in 19 patients, and 131 patients with AF but without HCM were studied retrospectively. Primary endpoints (ischemic strokes or cardiac death, whichever occurred first) and ischemic strokes were examined by Kaplan-Meier curves. In the patients with HCM, the primary endpoints occurred more frequently in those with AF than in those without AF (event rate at 5 years 23.0% vs 12.3%, p<0.01). Similarly, the frequency of ischemic strokes in HCM was also much higher with AF than without AF (23.0% vs 5.9% at 5 years, p<0.01). According to multivariate Cox analysis, the strong independent risk factor for ischemic strokes in HCM was AF (p<0.01), whereas in patients with AF they were HCM (p<0.01) and age (p<0.01). These results suggest that incidence of ischemic strokes in HCM is markedly increased if complicated by AF as compared with that in patients with AF alone.
- 社団法人日本循環器学会の論文
- 1997-07-20
著者
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Kinoshita Masahiko
First Department of Internal Medicine, Shiga University of Medical Science
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Kinoshita Masahiko
Division Of Cardiology Department Of Medicine Shiga University Of Medical Science
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Nakamura Yasuyuki
First Department of Internal Medicine, Shiga University of Medical Science
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Yoshida Michiaki
First Department of Internal Medicine, Shiga University of Medical Science
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Higashikawa Masahito
First Department of Internal Medicine, Shiga University of Medical Science
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Nakamura Yasuyuki
Heart Rhythm Center Department Of Cardiovascular Medicine Shiga University Of Medical Science
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Yoshida Michiaki
Department Of Health Science Shgia University Of Medical Science
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Murakami Yoshitaka
Department Of Health Science Shiga University Of Medical Science
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Kinoshita Masahiko
First Department Of Internal Medicine
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Murakami Yoshitaka
Faculty Of Healthcare Kiryu University
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Murakami Yoshitaka
Fac. Of Healthcare Kiryu Univ.
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Klnoshita Masahiko
First Department Of Internal Medicine Shiga University Of Medical Science
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Higashikawa Masahito
Department Of Cardiology Kohoku General Hospital:first Department Of Internal Medicine Shiga Univers
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Nakamura Yasuyuki
First Department Of Internal Medicine Shiga University Of Medical Science
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