Plasma Cardiac Natriuretic Peptides as Biochemical Markers of Recurrence of Atrial Fibrillation in Patients With Mild Congestive Heart Failure
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概要
- 論文の詳細を見る
To determine changes in plasma brain natriuretic peptide (BNP) after direct current cardioversion (DC) and to evaluate the relationship between plasma atrial natriuretic peptide (ANP) and BNP and the recurrence of atrial fibrillation (AF) after DC in patients with mild congestive heart failure (CHF), plasma ANP and BNP were measured before and after DC in 71 patients with mild CHF and then followed. In 65 patients with successful DC, both ANP and BNP decreased 15 min after DC. Cox stepwise multivariate analysis among 14 variables such as age, history of AF, echocardiographic parameters, medication and ANP and BNP revealed that only low ANP (p=0.005) and high BNP before DC (p=0.0002) were independent predictors of recurrent AF. A ratio of ANP to BNP less than 0.44 was a significant risk factor for AF recurrence by Kaplan-Meier analysis (p=0.02). BNP began to decrease immediately after successful DC. High BNP and relatively low ANP compared with BNP were independent risk factors of AF recurrence in patients with mild CHF.
- 社団法人日本循環器学会の論文
- 2000-09-20
著者
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Kinoshita Masahiko
First Department of Internal Medicine, Shiga University of Medical Science
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Maeda Keiko
First Department Of Internal Medicine Shiga University Of Medical Science
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Tsutamoto Takayoshi
First Department of Internal Medicine, Shiga University of Medical Science
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Mabuchi Naoko
First Department of Internal Medicine, Shiga University of Medical Science
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Tsutamoto Takayoshi
Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science
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Kinoshita Masahiko
The First Department Of Internal Medicine Shiga University Of Medical Science
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Kinoshita Masahiko
First Department Of Internal Medicine Shiga University Of Medical Science
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Kinoshita Masahiko
First Department Of Internal Medicine
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Tsutamoto Takayoshi
First Department Of Internal Medicine Shiga University Of Medical Science
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Mabuchi Naoko
First Department Of Internal Medicine Shiga University Of Medical Science
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Kinoshita M
First Department Of Internal Medicine Shiga University Of Medical Science
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