Quantification of myocardial perfusion SPECT using freeware package (cardioBull)
スポンサーリンク
概要
- 論文の詳細を見る
Objective: We have developed freeware package for automatically quantifying myocardial perfusion and 123I-labeled radiopharmaceutical single-photon emission computed tomography (SPECT), which is called "cardioBull". We aim to evaluate diagnostic performance of the detection of coronary artery disease (CAD) on the developed software in comparison with commercially available software package [Quantitative Perfusion SPECT (QPS)]. Methods: Stress-rest 99mTc-sestamibi myocardial perfusion SPECT was performed in 36 patients with CAD and 35 control patients. A ≥75% stenosis in the coronary artery was identified by coronary angiography in the CAD group. Segmental perfusion defect score was automatically calculated by both cardioBull and QPS software. Summed stress score (SSS) was obtained to detect CAD by the receiver operator characteristic (ROC) analysis. Areas under the ROC curves (AUC) were calculated in patient-based and coronary-based analyses. Results: Mean SSSs showed no significant difference between cardioBull and QPS (6.0 ± 7.1 vs. 5.6 ± 7.0). The AUC for cardioBull was equivalent to that for QPS (0.91 ± 0.04 vs. 0.87 ± 0.04, p = n.s.). Sensitivity, specificity, and accuracy for cardioBull were 89, 74, and 82%, respectively. For the regional detection of CAD, the AUC showed largest value in left anterior descending coronary artery (LAD) territory (0.86 ± 0.06 for cardioBull, 0.87 ± 0.06 for QPS, p = n.s.). Sensitivity, specificity and accuracy of cardioBull were 70, 88, and 83% for the LAD; 91, 62, and 66% for the left circumflex coronary artery (LCx); and 78, 69, and 70% for the right coronary artery (RCA), respectively. Conclusions: The AUC, sensitivity, specificity and accuracy for the detection of CAD showed high diagnostic performance on the developed software. In addition, the developed software provided comparable diagnostic performance to the commercially available software package. © 2011 The Japanese Society of Nuclear Medicine.
- Springer Verlag (Germany) / 日本核医学会 = the Japanese Society of Nuclear Medicineの論文
- 2011-10-01
著者
-
滝 淳一
金沢大学医学部核医学科
-
絹谷 清剛
金沢大学バイオトレーサ診療学
-
NAKAJIMA Kenichi
Department of Biotracer Medicine, Kanazawa University Graduate School of Medical Sciences
-
Kinuya Seigo
金沢大学 自然科学研究科
-
Kinuya Seigo
Graduate School Of Medical Sciences Kanazawa University
-
Nakajima Kenichi
Kanazawa Univ. Hospital Kanazawa Jpn
-
Kawano Masaya
Department of Nuclear Medicine, Kanazawa University Hospital
-
Kinuya Seigo
金沢大学 医学系研究科バトオトレーサー診療学
-
絹谷 清剛
金沢大学医学部
-
Kuniya S
Kanazawa Univ. School Of Medicine Kanazawa
-
Matsuo S
Department Of Nuclear Medicine Kanazawa University Hospital
-
Matsuo Shinro
滋賀医科大学 内科学第一
-
Matsuo Shinro
滋賀医科大学 呼吸循環器内科
-
Matsuo Shinro
Kanazawa Univ. Hospital Kanazawa Jpn
-
Matsuo Shinro
Department Of Nuclear Medicine Kanazawa University Hospital
-
Matsuo Shinro
Department Of Cardiovascular And Respiratory Medicine Shiga University Of Medical Science
-
Matsuo Shinro
日本大学 医学部循環器内科部門
-
Taki J
Department Of Nuclear Medicine Kanazawa University Hospital
-
Taki Junichi
先端医学薬学研究センター
-
Shiba Kazuhiro
Radioisotope Center Kanazawa University
-
Kitamura Masaru
Department Of Radiology Kanazawa Cardiovascular Hospital
-
Taki Junichi
Kanazawa University Hospital
-
Taki Junichi
Department Of Biotracer Medicine Kanazawa University Graduate School Of Medical Science
-
KAWANO Masaya
Kanazawa Cardiovascular Center
-
Okuda Koichi
Department Of Biotracer Medicine Kanazawa University
-
Kinuya Seigo
Department Of Biotracer Medicine Kanazawa University Graduate School Of Medical Sciences
-
Taki Junichi
Department Of Nuclear Medicine Kanazawa University Hospital
-
Nakajima Kenichi
Kanazawa Univ. Kanazawa Jpn
-
Nakajima Ken-ichi
Department Of Nuclear Medicine Kanazawa University Hospital
-
Kinuya Keiko
Department Of Nuclear Medicine Kanazawa University Hospital
-
Kinuya S
Department Of Nuclear Medicine Kanazawa University School Of Medicine
-
絹谷 清剛
金沢大学医学部核医学科
-
Hosoya Tetsuo
Department Of Clinical Application Technology Daiichi Radioisotope Laboratories Ltd.
-
Kawashiri Masaaki
Division Of Cardiovascular Medicine Kanazawa University Graduate School Of Medical Science
-
Nakajima Kenichi
Kanazawa University Hospital
-
Matsuo Shinro
Division Of Cardiology Department Of Medicine Shiga University Of Medical Science
-
Hosoya Tetsuo
Fujifilm Ri Pharma
-
Kawashiri Masa-aki
Department Of Internal Medicine And Molecular Genetics Of Cardiovascular Disorders Division Of Cardi
-
Kanayama Sugako
Department Of Nuclear Medicine Kanazawa University Hospital
-
Nakajima Kenichi
Department Of Nuclear Medicine
-
Kawashiri Masaaki
Division Of Cardiovascular Medicine Kanazawa University Graduate School Of Medicine
-
ISHIKAWA Takehiro
Fujifilm RI Pharma Co., Ltd
-
Kubota Masahiro
Department Of Radiology Weill Cornell Medical College Of Cornell University
-
Taki Junichi
Department Of Nuclear Medicine Kanazawa University School Of Medicine
-
Nakajima Kenichi
金沢大学附属病院 核医学
-
Ishikawa Takehiro
Fujifilm Ri Pharma Co. Ltd
関連論文
- 12) VESTと色素希釈法による心拍出量測定の比較
- 虚血性心疾患における安静時^I-BMIPP心筋シンチグラフィの意義 : ^Tl-運動負荷心筋シンチグラフィとの比較検討
- Attenuation correction of myocardial SPECT by scatter-photopeak window method in normal subjects
- 再発・難治性低悪性度B細胞リンパ腫(B-NHL)に対する ^Y-ibritumomab tiuxetan 第II相試験における ^In-ibritumomab tiuxetan のシンチグラムの読影判定
- ^Tc-sestamibi to monitor treatment with antisense oligodeoxynucleotide complementary to MRP mRNA in human breast cancer cells
- Asialoglycoprotein receptor concentration in tumor-bearing livers and its fate early after their sectorial resection
- Intraperitoneal radioimmunotherapy in treating peritoneal carcinomatosis of colon cancer in mice compared with systemic radioimmunotherapy
- Experimental radioimmunotherapy with ^186 Re-MAG3-A7 anti-colorectal cancer monoclonal antibody : Comparison with ^131 I-counterpart
- Enhanced Efficacy of Radioimmunotherapy Combined with Systemic Chemotherapy and Local Hyperthermia in Xenograft Model
- Rhenium-186-mercaptoacetyltriglycine-labeled Monoclonal Antibody for Radioimmunotherapy : In vitro Assessment, in vivo Kinetics and Dosimetry in Tumor-bearing Nude Mice
- 多施設による ^Tc-MAG_3 腎機能定量解析精度の検討
- 慢性虚血性心疾患の診断と病態把握のための検査法の選択基準に関するガイドライン : 平成10年度報告 慢性虚血性疾患の診断における各種検査法の意義 : 平成11年度報告 慢性虚血性心疾患の病態と診断目的に基づいた検査計画法(循環器病の診断と治療に関するガイドライン(1998-1999年度合同研究班報告))
- 慢性虚血性心疾患の診断と病態把握のための検査法の選択基準に関するガイドライン
- 0936 肥大型心筋症における^I-MIBG心筋シンチ所見と長期予後 : ^Thallium心筋シンチ所見との比較
- ^Tc-tetrofosmin RI アンジオグラフィを用いた運動負荷時心筋血流増加率測定法
- ^Tc-tetrofosminを用いた運動負荷時心筋摂取増加率による虚血性心疾患の評価
- 類腱線維腫手術16年後同部位に発生した大腿骨遠位部骨肉腫の1例
- 0303 ATP負荷^Tc-MIBI心筋シンチグラフィによる冠血流予備能の評価 : ドップラーフローワイヤーとの比較
- 乳癌における sentinel node の核医学的検出 : 方法, 意義, 留意点
- 日本人における心筋SPECTデータの標準化
- 最終報告 : 1. 日本人における心筋SPECTデータの標準化
- 日本人における心筋SPECTデータの標準化(2年間)
- 骨軟部病変の ^Tc-MIBI による評価 : ^Tl との比較ならびに化学療法の治療効果との関連について
- 心筋SPECT標準(JSNM2007)の作成と臨床的検証
- ^Tc-Tetrofosminを用いた^Tc-Pyrophoshate急性心筋梗塞シンチグラフィ : 集積部位診断能の向上
- Esophageal transit scintigraphy and structured questionnaire in patients with systemic sclerosis with endoscopically proven reflux esophagitis
- PJ-630 Clinical Usefulness of Fusion Imaging System by Using 64-Section MDCT and Cardiac SPECT(PJ106,Nuclear Cardiology (Others) (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-099 Significance of C-11 Hydroxyephedrine Washout in Patients with Heart Disease(PJ017,Nuclear Cardiology (PET) (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- FRS-048 Temporal Assessment of Tenascin-C Expression after Myocardial Ischemia and Reperfusion using I-125-anti Tenascin-C Antibody(FRS10,Updates in Nuclear Cardiology (I),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japan
- PJ-359 Japanese Normal Values of Cardiac Volumes and Functional Parameters Derived from QGS Program : A Comparison with European Population(Nuclear cardiology(08)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation S
- 99mTc-Annexin-V uptake in a rat model of variable ischemic severity and reperfusion time
- PE-364 Preliminary Report of a Multicenter Cohort Study of Myocardial Viability Assessment by Gated^Tc-Sestamibi SPECT at Rest(Nuclear cardiology-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- 循環器SPECTの最新トピックス (特集 核医学の最前線)
- Myocardial Damages in Systemic Sclerosis Detected by Gated Myocardial Perfusion SPECTand Sympathetic Imaging
- Fluctuation of adenosine concentration by modes of intravenous infusion based on mathematical simulation and experiments
- PJ-643 Prediction of Cardiac Events in Patients with Hypertrophic Cardiomyopathy : Usefulness of MIBG Myocardial Scintigraphy(Cardiomyopathy, basic/clinical-7 (M) PJ108,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japane
- PE-510 Relationship between Serum Markers of Atherosclerosis and Vascular FDG Uptake in Volunteers(Nuclear cardiology-2 (I) PE86,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PE-275 Fluctuation of Adenosine Concentration through Single Intravenous Infusion Line Based on Mathematical Simulation and Experiments(Nuclear cardiology-3 (I) PE46,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese C
- FRS-019 Ischemic Post-conditioning Reduces Tc-99m-annexin V Uptake in Rat Hearts(Advances in Nuclear Cardiology-1 (I) FRS4,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- 心臓核医学とEBM (特集2 核医学の最新トピックス)
- Characterization of cartilaginous tumors with ^Tl scintigraphy
- Accuracy of cardiac PET imaging using post-injection transmission scan
- Failure of radioiodine treatment in Graves' disease intentionally caused by a patient : Suspected Munchausen syndrome
- Brown adipose tissue : Evaluation with ^Tl and ^Tc-sestamibi dual-tracer SPECT
- Left ventricular ejection and filling rate measurement based on the automatic edge detection method of ECG-gated blood pool single-photon emission tomography
- Multifactorial analysis on the short-term side effects occurring within 96 hours after radioiodine-131 therapy for differentiated thyroid carcinoma
- 心臓核医学による心筋虚血診断の最新動向 (特集 冠動脈プラークと冠動脈狭窄・心筋虚血診断の最前線)
- Preliminary evaluation of image reconstruction by ordered-subset expectation maximization in thallium-201 lung scintigraphy
- Discrepant uptake between fluorine-18 fluorodeoxy glucose and Tc-99m sestamibi in bronchioloalveolar cell carcinoma
- Comparison of Left Ventricular Volumes and Ejection Fraction between ECG-Gated N-13 Ammonia PET and MRI in Patients with Myocardial Infarction
- Comparison between ECG-Gated FDG and NH3 PET for the Assessment of Left Ventricular Function in Patients with Myocardial Infarction
- 99mTc-tetrofosmin uptake in bone metastases from breast cancer
- P596 冠動脈疾患におけるATP負荷Tc-99m MIBI心筋シンチグラフィの検討 : 運動負荷法との比較
- 劇症肝炎における99mTc-Sn-colloidの腎描画 予後不良所見かアーチファクトか?
- P706 低容量ドブタミン負荷心プールシンチグラフィによる壁運動改善の予測 : TI再静注法との比較
- ^Tc-ECDのBrain Uptake Ratioを用いた,新しい非侵襲的局所脳血流量測定法の考案 : カメラ差の較正と小視野型カメラヘの適応
- SF-063-2 RI法で同定されたセンチネルリンパ節における,RIコロイドのリンパ節内局在の描出
- 1023 高血圧心における動的運動時の左室機能不全とその回復遅延
- オートラジオグラフィーを用いて画像化したRIコロイドの節内分布からみた, 胃癌RI法センチネルリンパ節生検における, フチン酸とスズコロイドの比較(第105回日本外科学会定期学術集会)
- Respiratory distress caused by radioiodine therapy in patients with differentiated thyroid cancer
- ^I-MIBG治療
- Single dose planning for radioiodine-131 therapy of Graves' disease
- ^Tc標識心筋血流製剤を用いた初回循環時法による心肺出量の推定法
- 心電図同期心筋 SPECT 解析プログラムによる心機能指標のファントムおよび臨床例における検討
- Triple Energy Window法による散乱補正が心筋SPECTの定量に及ぼす影響および2核種収集への応用
- 左肺動脈欠損症における肺血流の評価 : RI アンギオグラフィ有用性
- The validity of multi-center common normal database for identifying myocardial ischemia: Japanese Society of Nuclear Medicine Working Group Database
- P738 肥大型心筋症における運動時血圧反応とその回復
- 0991 高血圧心における運動時左室挙動とそれに対するdiltiazemの効果 : 携帯型持続心機能モニター(VEST)を用いて
- MIBGシンチグラフィの基礎と臨床応用
- 反射性交感神経性ジストロフィー(RSD)の骨シンチグラフィ
- Transient Dilation of the Left Ventricule Using ATP Stress N-13 NH_3 PET in Patients with Coronary Artery Disease
- The Correlation between Technetium 99m-Sestamibi Myocardial Scintigraphy and Mitochondrial Cytochrome Oxidase Activity in Dilated Cardiomyopathy
- Hypoxic Preconditioning Induces the Expression of Heme Oxygenase-1 via P38 Mitogen-Activated Protein Kinase (p38MAPK) Pathway in Cardiac Fibroblasts
- Global and Regional Left Ventricular Function Assessed by ECG-Gated N-13 Ammonia PET in Patients with Coronary Artery Disease
- 陳旧性心筋梗塞例におけるTl再静注でFill-inを示す心筋での脂肪酸代謝に関する検討
- 色素性絨毛結節性滑膜炎 (PVNS) の核医学的検査所見
- Creation and characterization of Japanese standards for myocardial perfusion SPECT: database from the Japanese Society of Nuclear Medicine Working Group
- P716 Tc-99m標識心筋血流製剤のためのRIアンジオグラフィによる心拍出量の算出法の確立
- Clinical usefulness of novel cardiac MDCT/SPECT fusion image
- P283 TI-201心筋SPECTにおける散乱補正と減弱補正の与える定量的影響
- 0944 I-123-MIBGによるParkinson's diseaseにおける心交感神経機能異常の評価
- 0749 Tc-99m tetrofosmin RIアンジオグラフィによる運動負荷時心筋血流増加比算出法の確立
- P465 冠動脈バイパス手術後の心電図同期心筋SPECTによる心機能評価 : 中隔側奇異運動の出現の意味
- 心電図同期心筋 SPECT による冠動脈バイパス手術後の局所機能指標の定量的検討
- Thallium-201 負荷心筋 SPECT による冠動脈バイパス術 (CABG) 後の血流評価
- SPECTによる心筋代謝の評価
- 心筋のメモリーイメージング
- 心筋虚血検出における負荷検査の基礎
- 心電図同期Gated SPECTの現状と今後の課題 (特集 21世紀の核医学--優しい先進医療をめざして)
- 心臓核医学における定量解析の位置づけと今後の展望 (特集 核医学の新たな展開)
- 心電図同期心筋 SPECT 解析による局所収縮機能指標の検討
- SPECT による心筋 viability の評価
- 仮骨延長法における化学療法下の仮骨形成能について
- 0279 肥大型心筋症におけるQT dispersionと心臓交感神経機能
- T1-SPECTによる肺病変の質的診断 : 小病変における役割 : ワークショップ1 : 肺末梢小型陰影の画像診断
- Use of ^Tc-MIBI scintigraphy in the evaluation of the response to chemotherapy for osteosarcoma : comparison with ^Tl scintigraphy and angiography
- Assessment of Doxorubicin Cardiac Toxicity Using Gated ^Tc-Hexakis-2-Methoxyisobutylisonitrile Myocardial Single Photon Emission Computed Tomography : Wall Thickening and Motion Abnormalities Can Be an Early Sign of Cardiac Involvement
- Quantification of myocardial perfusion SPECT using freeware package (cardioBull)
- VEST による無症候性心筋虚血の評価