ASSESSMENT OF Left Ventricular Relaxation in the Diseased Heart in Man : SYMPOSIUM ON HEART MECHANICS IN DIASTOLE
スポンサーリンク
概要
- 論文の詳細を見る
To examine the exponential nature of the left ventricular pressure (LVP) fall during isovolumic relaxation (IRP) in 59 patients (normal (N), 6; angina pectoris (AP), 13; myocardial infarction (MI), 24; and congestive (CCM, 6) and hypertrophic (HCM, 10) cardiomyopathies), LVP and dP/dt were measured by a Millar's catheter-tipped transducer. In P vs time relation during IRP was reasonably fitted by a straight line (r > 0.97) in all cases. Time constant (msec) in CCM (56.9 ± l0.7), HCM (44.8 ± 12.4) and MI (43.8 ± 7.4) was higher (p < 0.05) than in N (30.3 ± 5.5), and peak (-) dP/dt (mmHg/sec) was lower (841 ± 171, 1152 ± 397 and 1270 ± 21 1, respectively; p < 0.05) than in N (1885 ± 150), suggesting impaired LV relaxation in these groups. However, (-) dP/dt upstroke pattern was exponential only in both N and 8 of the AP. The (-) dP/dt upstoke in the remaining groups lost its exponential nature, showing rather a downward-convex curvature which was especially prominent in CCM. This indicates non-exponential fall of LVP during IRP. Thus, the present results suggest that impaired relaxation disturbs the exponential nature of LV relaxation.
- 社団法人日本循環器学会の論文
- 1982-01-20
著者
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Kawamura K
Department Of Internal Medicine (iii) Osaka Medical College
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MATSUZAKI Masunori
the Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Katayama Kazuhiro
The Second Department of Interial Medicine, Yamaguchi University School of Medicine
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KAWAMURA Keishiro
Kyoto Univ.
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KUSUKAWA Reizo
The second Department of Internal Medicine, Yamaguchi University School of Medicine
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MATSUDA YASUO
The Second Department of Internal Medicine, University of Yamaguchi
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Matsuzaki Masunori
Department Of Medicine And Clinical Science Division Of Cardiology Yamaguchi University Graduate Sch
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Kawamura Keishiro
The Third Division Department Of Medicine Osaka Medical College
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KUMADA TOSHIAKI
The Second Department of Internal Medicine, Yamaguchi University School of Medicine
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Kumada Toshiaki
The Third Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Kumada Toshiaki
The 3rd Medical Clinic Kyoto University Hospital
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Kumada Toshiaki
Department Of Internal Medicine Yamaguchi University School Of Medicine
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Kaziwara Ko
Department Of Cardiology Tenri Hospital
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Matsuda Yasuo
The Second Division Department Of Internal Medicine Yamaguchi University School Of Medicine
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Kusukawa Reizo
The Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Kumada Toshiaki
The Division Of Internal Medicine Yamaguchi University School Of Medicine
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Mori Masaki
Division Of Gene Therapy Science Osaka University
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Matsuzaki Masunori
The Second Department Of Internal Medicine University Of Yamaguchi
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Kusukawa Reizo
Department Of Cardiology Tenri Hospilal
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Matsuda Yasuo
Department Of Cardiovascular Medicine Yamaguchi University Graduate School Of Medicine
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Yano Masafumi
Department Of Cardiovascular Medicine Yamaguchi University School Of Medicine
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Kajiwara Ko
3rd Div. Dept Of Intern. Med. And 2nd Div. Dept Of Surg. Kyoto Univ. Faculty Of Med.
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Kumada Toshiaki
The Second Department Of Internal Medicine Yamaguchi University School Of Medicine
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Katayama Kazuhiro
2nd Dept. Of Internal Med. Yamaguchi University
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