Toxoplasmic Encephalitis in Patients with Acquired Immunodeficiency Syndrome : Four Case Reports
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概要
- 論文の詳細を見る
Four patients, all males aged 40-64 years, presented with toxoplasmic encephalitis associated with human immunodeficiency virus(HIV)infection manifesting as nonspecific neurological deficits such as epilepsy or hemiparesis.Magnetic resonance imaging showed single or multiple lesions with ring enhancement, mimicking metastatic brain tumor or brain abscess.Marked eosinophilia was noted in three patients.Two patients who received anti-toxoplasma chemotherapy in the early stage had a good outcome.However, the other two patients suffered rapid neurological deterioration and needed decompressive surgery, resulting in a poor outcome.Toxoplasma diffusely infects the whole central nervous system from the early stage.The outcome for patients who needed emergency surgery was poor.Therefore, this rare but increasingly common infectious disease must be considered in the differential diagnosis of a patient with neuroimaging findings similar to those of metastatic tumor or brain abscess.Appropriate chemotherapy should be started immediately after HIV-positive reaction is identified in patients with single or multiple mass lesions with ring enhancement.
- 日本脳神経外科学会の論文
- 2000-02-15
著者
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WATANABE Osamu
Department of Surgery, Tokyo Women's Medical University Daini Hospital.
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YANO Akihiko
Department of Infection and Host Defense, Graduate School of Medicine, Chiba University
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Saeki Naokatsu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Yano Akihiko
Department Of Infection And Host Defense Chiba University
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Yano Akihiko
Departments Of Parasitology Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurosurgery Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurological Surgery Chiba University School Of Medicine
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NAKAZAKI Susumu
Departments of Neurological Surgery, Chiba University School of Medicine
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ITOH Seiro
Departments of Neurological Surgery, Chiba University School of Medicine
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OSATO Katsunobu
Departments of Neurological Surgery, Chiba University School of Medicine
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HAMADA Norikazu
Departments of Neurological Surgery, Chiba University School of Medicine
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MITSUHASHI Hiromitsu
Departments of Neurological Surgery, Chiba University School of Medicine
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SHIN Hideo
Departments of Neurological Surgery, Chiba University School of Medicine
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KIUCHI Ichirou
Departments of Neurological Surgery, Chiba University School of Medicine
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KOBAYASHI Chizuko
Departments of Parasitology, Chiba University School of Medicine
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Itoh Seiro
Departments Of Neurological Surgery Chiba University School Of Medicine
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Shin Hideo
Departments Of Neurological Surgery Chiba University School Of Medicine
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Shin Hideo
Department Of Neurological Surgery Chiba University School Of Medicine
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Kiuchi Ichirou
Departments Of Neurological Surgery Chiba University School Of Medicine
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Nakazaki Susumu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Osato Katsunobu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Hamada Norikazu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Kobayashi Chizuko
Departments Of Parasitology Chiba University School Of Medicine
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Kobayashi Chizuko
Department Of Internal Medicine Chiba National Hospital
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Mitsuhashi Hiromitsu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Watanabe Osamu
Department Of Surgery Tokyo Women's Medical University Daini Hospital
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Saeki Naokatsu
Department Of Neurological Surgery
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Yamaura Akira
Departments Of Neurological Surgery Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurological Surgery
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Watanabe Osamu
Department Of Earth And Planetary Science Kyushu University
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Watanabe Osamu
Departments Of Neurological Surgery Chiba University School Of Medicine
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Watanabe Osamu
Department Of Computer Science And Systems Engineering Muroran Institute Of Technology
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Watanabe Osamu
Department of Applied Chemistry, Faculty of Engineering, Yamagata University
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