Effects of a Respiratory Stimulant on Intracranial Pressure and Cerebral Blood Flow
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概要
- 論文の詳細を見る
The main cause of sudden death in patients with intracranial hypertension is respiratory failure. This study was a search for a clue to respiratory treatment which could be used at the scene of an accident. For this purpose, intravenous administration of respiratory stimulants was thought to be the most simple measure. Doxapram hydrochloride (Doxapram) was used to stimulate respiration impaired by balloon-induced intracranial hypertension in cats. Intravenous administration of Doxapram resulted in sufficient respiratory stimulation at the dose of 1.0 mg/kg, but could not decrease PaCO_2 lower than 25 torr. In 4 out of 10 cats, administration of Doxapram improved the respiratory condition and increased cerebral perfusion pressure and regional cerebral blood flow. Further investigation was required to find the best timing of Doxapram administration to maximize life preservation.
- 日本脳神経外科学会の論文
- 1983-07-15
著者
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Makino Hiroyasu
Department Of Neurological Surgery Chiba University School Of Medicine
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Makino H
Department Of Neurological Surgery School Of Medicine Chiba University
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Yamaura A
Department Of Neurological Surgery Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurosurgery Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurological Surgery Graduate School Of Medicine Chiba University
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Yamaura Akira
Department Of Neurological Surgery Chiba University School Of Medicine
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NAMBA Hiroki
Department of Neurosurgery, Hamamatsu University School of Medicine
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Namba Hiroki
Department Of Neurological Surgery School Of Medicine Chiba University
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AKIMOTO Masaru
Department of Neurological Surgery, Chiba University School of Medicine
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HAGIHARA Yashiro
Department of Brain Research Institute, Chiba University School of Medicine
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SAKURAI Koich
Department of Brain Research Institute, Chiba University School of Medicine
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Sakurai Koich
Department Of Brain Research Institute Chiba University School Of Medicine
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Akimoto Masaru
Department Of Neurological Surgery Chiba University School Of Medicine
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Yamaura Akira
Department Of Neurological Surgery
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Makino Hiroyasu
Department Of Neurological Surgery Chiba Unibersity
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Hagihara Yashiro
Department Of Brain Research Institute Chiba University School Of Medicine
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