Gliomatosis Peritonei を伴った小児卵巣未熟奇形腫の1例

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We reported a case of immature teratoma of the ovary with gliomatosis peritonei. A ten-year-old girl was admitted to our hospital for evaluation of an abdominal mass. On physical examination a huge mass was palpable in the lower abdomen. Serum alpha-fetoprotein (17.8ng/ml) and CA125 (300U/ml) levels were elevated. At laparotomy, a large left ovarian tumor with adhesion to the omentum was found, and multiple white nodules were present on the surface of omentum and peritoneum. The primary tumor weighed l,535g and measured 18X15X9 cm. Histological diagnosis of ovarian solid tumor was grade 1 immature teratoma. The omental and peritoneal implants were composed exclusively of mature glial tissue (grade 0). After operation, she was treated with combination of cisplatin, vinblastine, and peplomycin (PVP) for four courses. She has been doing well for 15 months postoperatively. Gliomatosis peritonei is a rare complication of ovarian teratomas. Twenty-one cases of gliomatosis peritonei in children, including the present case, were reported in Japan. Fifteen cases were immature ovarian teratoma, and 6 mature teratoma. All of 16 cases described in prognosis were alive and well from 7 months to 21 years after the operation. It is suggested that gliomatosis peritonei associated with ovarian teratoma has a favorable prognosis.
日本小児外科学会の論文
1991-08-20