"B-1 Pharmacokinetic Study Of Tris(2-chloroethyl)phosphate (TCEP) in Rats After inhalation.
スポンサーリンク
概要
- 論文の詳細を見る
- 日本トキシコロジー学会の論文
- 1996-12-20
著者
-
Ohno Yasuo
National Institute of Health Sciences
-
TAKAHASHI Atsushi
National Institute of Hygienic Sciences
-
Kurebayashi Hideo
National Institute Of Health Sciences
-
Minegishi Ken-ichiro
National Institute Of Health Sciences
-
Esumi Yoshio
Daiichi Pure Chemicals Co. Ltd.
-
Esumi Yoshio
Tokai Laboratories Daiichi Pure Chemicals Co. Ltd.
-
Takahashi Atsushi
National Institute Of Health Sciences
-
Ninomiya Shin-ichi
Daiichi Pure Chemicals Co. Ltd.
-
Yoshida Kenji
Tokai Research Laboratories, Daiichi Pure Chemicals Co., LTD.
-
Ninomiya Shin-ichi
Tokai Research Laboratories, Daiichi Pure Chemicals Co., LTD.
-
Ohno Yasuo
National Inst. Of Health Sci. Tokyo Jpn
-
Yoshida Kenji
Daiichi Pure Chemicals Co. Ltd.
-
Takahashi Atsushi
National Institute Of Advanced Industrial Science And Technology
関連論文
- Assessment of the human Cell Line Activation Test (h-CLAT) for Skin Sensitization ; Results of the First Japanese Inter-laboratory Study
- Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population
- 日本人におけるGSTT1及びGSTM1の遺伝子多型の同定及びハプロタイプ構造の解析
- Genetic Variations of VDR/NR1I1 Encoding Vitamin D Receptor in a Japanese Population
- Genetic Variations and Frequencies of Major Haplotypes in SLCO1B1 Encoding the Transporter OATP1B1 in Japanese Subjects : SLCO1B1^*17 is More Prevalent Than ^*15
- Expression of CYP2A6 in Tumor Cells Augments Cellular Sensitivity to Tegafur
- Three novel single nucleotide polymorphisms in UGT1A10
- Sequence-based Analysis of the CYP2D6^*36-CYP2D6^*10 Tandem-type Arrangement, a Major CYP2D6^*10 Haplotype in the Japanese Population
- 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
- 21C-03-3 Effects of Diphenyl on Hepatic Peroxysomal Enzyme and Drug-Metabolizing Enzyme Activities in BDF1 Mice.
- Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
- 2C-17 Effects of Substituted Phenylurea Pesticides and Their Metabolites in Freshly Isolated and Cultured Rat Hepatocytes.
- "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
- EFFECT OF CARBAMATES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
- EFFECT OF CARBAMATES ON RAT FRESHLY ISOLATED HEPATOCYTES
- Collaborative work on evaluation of ovarian toxicity by repeated-dose and fertility studies in female rats
- Gene Expression Property of High-Density Three-Dimensional Tissue of HepG2 Cells Formed in Radial-Flow Bioreactor(BIOINFORMATICS)
- Three-Dimensional High-Density Culture of HepG2 Cells in a 5-ml Radial-Flow Bioreactor for Construction of Artificial Liver(Biochemical Engineering)
- 日本人で新たに見いだされた低活性型CYP2D6ハプロタイプ
- Morphological characterization of the ovary under normal cycling in rats and its viewpoints of ovarian toxicity detection
- Safety assessment of biopharmaceuticals : Japanese perspective on ICH S6 guideline maintenance
- CURRENT OPINION : SAFETY EVALUATION OF DRUG METABOLITES IN DEVELOPMENT OF PHARMACEUTICALS
- URINALYSIS FOR DETECTION OF CHEMICALLY INDUCED RENAL DAMAGE (2) : Changes in urinary excretions of enzymes and various components caused by p-aminophenol, puromycin aminonucleoside and hexadimethrine
- URINALYSIS FOR DETECTION OF CHEMICALLY INDUCED RENAL DAMAGE (1) : Changes in urinary excretions of enzymes and various components caused by mercuric chloride and gentamicin
- CYP3A4 Gene Polymorphisms Influence Testosterone 6β-hydroxylation
- Results of a Japanese ring study of a Human Cell Line Activation Test (h-CLAT) for predicting skin sensitization potential (1st report)
- P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
- COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
- Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
- Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity
- Problems with Registration-Directed Clinical Trials for Lung Cancer in Japan
- Phase I study of cisplatin, vinorelbine, and concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer
- Tumor response to chemotherapy : The validity and reproducibility of RECIST guidelines in NSCLC patients
- Prospective Evaluation of the Feasibility of Cisplatin-based Chemotherapy for Elderly Lung Cancer Patients with Normal Organ Functions
- Synthesis of High-silica CHA Zeolite from FAU Zeolite in the Presence of Benzyltrimethylammonium Hydroxide
- 21C-01-3 Genetic polymorphisms of carcinogen-activating human phenol sulfotransferase and arylamine n-acetyltransferase, and urothelial cancer susceptibiltiy.
- Effects of pre-culture conditions on the human Cell Line Activation Test (h-CLAT) results : Results of the 4^ Japanese inter-laboratory study
- A study on serum difference on test results in the human Cell Line Activation Test (h-CLAT) : Results of 3^ Japanese inter-laboratory study
- A Study of the Criteria for Selection of THP-1 Cells in the Human Cell Line Activation Test (h-CLAT) : Results of 2^ Japanese Inter-laboratory Study
- JaCVAM statement on new alternatives to animal testing
- Review of an alternative to animal testing for safety evaluation of Quasi-drug
- "C-5 Validation of alternatives to eye irritation tests for cosmetic ingredients (Results of the first, second, and third validation).
- The Second Phase Validation Study of Alternative Methods to The Eye Irritation Test 11)Evaluation of EYTEX.
- THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 10)EVALUATION OF CYTOTOXICITY TEST ON CHL CELLS
- THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHOD TO THE EYE IRRITATION TEST 8.Evaluation of Cytotoxicity Test in SIRC Cells
- The second phase validation study of alternative methods to the eye irritation test (4) Evaluation of hemoglobin denaturation tests.
- The second phase validation study of alternative methods to the eye irritation test : Evaluation of Skin-squared ZK1100 and ZK1200 Models
- The second-phase validation of alternative methods to the eye irritation test. 9) Evaluation of cytotoxicity test on HeLa cells.
- THE SECOND PHASE OF VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 7) EVALUATION OF CYTOTOXICITY TESTS WITH Cornepack
- The second phase validation study of alternative methods to the eye irritation test (6)Evaluation of MATREX ^
- The second phase validation study of alternative methods to the eye irritation test for cosmetic ingredients 3) Evaluation of Hemolysis test.
- The second phase validation study of alternative methods to the eye irritation test (2) Evaluation of chorioallantoic membrane (CAM) tests.
- Results from Draize eye-irritation test and implications of their variations.
- Validation of alternative methods to eye irritaion test for safety evaluation of cosmetic ingredients, project and progress.
- Metabolism of 2,2,3,3,3-Pentafluoropropanol (5-FP) in Rats (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- Effect of Estradiol and Nonyiphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
- Suppressive Effect of p-Nonylphenol on Male-Specific mRNA Expression in the Embryonic Gonad of Chickens
- Effect of Estradiol and Nonylphenol on mRNA Levels of VitellogeninII in the Liver of Chicken Embryos
- Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
- Long-term follow-up of patients with unresectable locally advanced non-small cell lung cancer treated with chemoradiotherapy: A retrospective analysis of the data from the Japan Clinical Oncology Group trials (JCOG0003A)
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
- EFFECTS ON FETAL GROWTH OF REPEATED BLOOD COLLECTION FOR TOXICOKINETICS FROM PREGNANT RATS
- Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
- "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
- Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer
- Pharmacokinetic Study of Tris (2-chloroethyl) phosphate (TCEP) After Inhalation Exposure (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
- "B-2 Metabolic Study of Tris(2-Chloroethyl) Phosphate (TCEP) in vivo and in vitro.
- "B-1 Pharmacokinetic Study Of Tris(2-chloroethyl)phosphate (TCEP) in Rats After inhalation.
- LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
- MORPHINE METABOLISM IN ISOLATED HEPATOCYTES AND ITS IMPLICATIONS FOR HEPATOTOXICITY
- STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
- COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
- 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
- Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
- Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
- 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
- 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
- Disposition and Metabolism of 2-Nitro-p-cresol in Rats and Its Effect on Hepatic Ornithine Decarboxylase (Proceedings of the 12 th Symposium on Environmental Pollutants and Toxicology) (Regular Presentations)
- STUDIES ON THE ESTABLISHMENT OF APPROPRIATE SPERMATOGENIC ENDPOINTS FOR MALE FERTILITY DISTURBANCE IN RODENT INDUCED BY DRUGS AND CHEMICALS I. NITROBENZENE
- ENZYMATIC REDUCTION OF QUINONE DERIVED FROM BUTYLATED HYDROXYANISOLE IN RELATION TO ACTIVATING DIOXYGEN
- Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy
- Application of in vitro cytotoxicity test for alternative method to systemic toxicity in vivo : metabolic activation system and treatment period
- RELATIONSHIP BETWEEN UDP-GLUCURONOSYLTRANSFERASE ACTIVITY AND MICROSOMAL ENVIRONMENT
- Metabolism of Musk Xylene (MX) in Rats (Proceedings of the 16 th Symposium on Environmental Pollutants and Toxicology)
- Metabolic Fate of N, N'-Dimonomethylphenyl-p-phenylenediamine (DMPD) in a 2 Year Feeding Test (Proceedings of the 23rd Symposium on Toxicology and Environmental Health)
- STUDIES ON DEAMINATION MECHANISMS OF ALICYCLIC PRIMARY AMINES BY LIVER MICROSOMES WITH USE OF STABLE ISOTOPES
- Contribution of ICH on 3Rs in alternatives to animal experiments
- Toxicological bases for micro-dose study(Toxicological Bases for Micro-dose Study, Proceedings of the 32nd Annual Meeting)
- Significance of Japanese Center for the Validation of Alternative Methods (JaCVAM) Establishment
- Intrductory Remarks : REPEATED DOSE TISSUE DISTRIBUTION STUDIES (Repeated dose tissue distribution studies
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (7^ Report) : Evaluation of Volatile, Poorly Soluble Fragrance Materials
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (6^ Report) : A Study for Evaluating Oxidative Hair Dye Sensitization Potential Using h-CLAT
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (5^ Report) : A Study for Evaluating Preservative Skin Sensitization Potential Using h-CLAT
- Evaluation of DNA microarray results in the Toxicogenomics Project (TGP) consortium in Japan