The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (5^<th> Report) : A Study for Evaluating Preservative Skin Sensitization Potential Using h-CLAT

スポンサーリンク

概要

• 論文の詳細を見る
• 2010-10-31

著者

• Sakaguchi Hitoshi

  Safety Science Research Laboratories, Kao Corporation

• Okamoto Yuko

  資生堂

• Itagaki Hiroshi

  Shiseido Safety And Analytical Research Center

• Ashikaga Takao

  Shiseido Co. Ltd.

• Ashikaga Takao

  Shiseido Safety And Analytical Research Center

• OKAMOTO Kenji

  Kanebo Cosmetic Inc.

• SONO Sakiko

  Shiseido Co., Ltd.

• KUWAHARA Hirofumi

  Kanebo Cosmetic Inc.

• OKAMOTO Yuko

  KOSE Corporation

• Okamoto Kenji

  Kanebo Cosmetics Inc.

• Mizuno Makoto

  Kose Corporation

• Sakaguchi Hitoshi

  Kao Corporation

• Nakamura Tsuneaki

  Human & Environmental Safety Evaluation Center Lion Corporation

• Sono Sakiko

  Shiseido Co. Ltd.

• Kosaka Nanae

  Kao Corporation

• Suzuki Hiroyuki

  Kao Corporation Product Quality Management Division

• Ohno Yasuo

  National Inst. Of Health Sci. Tokyo Jpn

• Itagaki Hiroshi

  Safety And Analytical Research Center Shiseido Co. Ltd.

• Kishi Masataka

  Nippon Menard Cosmetic Co. Ltd.

• Itagaki Hiroshi

  Lion Corporation

• Kato Yoshinao

  Nippon Menard Cosmetic Co. Ltd.

• INABA Hiroyuki

  LION Corporation

• NAKAMURA Tsuneak

  Lion Corporation

関連論文

• Assessment of the human Cell Line Activation Test (h-CLAT) for Skin Sensitization ; Results of the First Japanese Inter-laboratory Study
• Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population
• Inter-laboratory study of short time exposure (STE) test for predicting eye irritation potential of chemicals and correspondence to globally harmonized system (GHS) classification
• 日本人におけるGSTT1及びGSTM1の遺伝子多型の同定及びハプロタイプ構造の解析
• Genetic Variations of VDR/NR1I1 Encoding Vitamin D Receptor in a Japanese Population
• Genetic Variations and Frequencies of Major Haplotypes in SLCO1B1 Encoding the Transporter OATP1B1 in Japanese Subjects : SLCO1B1^*17 is More Prevalent Than ^*15
• Expression of CYP2A6 in Tumor Cells Augments Cellular Sensitivity to Tegafur
• Three novel single nucleotide polymorphisms in UGT1A10
• Sequence-based Analysis of the CYP2D6^*36-CYP2D6^*10 Tandem-type Arrangement, a Major CYP2D6^*10 Haplotype in the Japanese Population
• 21C-03-4 Effects of 2-Mercaptobenzimidazole (MBI) and its methyl derivatives MMBI on rat hepatic drug metabolizing enzymes.
• 21C-03-3 Effects of Diphenyl on Hepatic Peroxysomal Enzyme and Drug-Metabolizing Enzyme Activities in BDF1 Mice.
• Sulfating-Activity and Stability of cDNA-Expressed Allozymes of Human Phenol Sulfotransferase, ST1A31 (^Arg) and ST1A32 (^His), Both of Which Exist in Japanese as Well as Caucasians^1
• 2C-17 Effects of Substituted Phenylurea Pesticides and Their Metabolites in Freshly Isolated and Cultured Rat Hepatocytes.
• "B-11 Effects of triazine herbicides on isolated and primary cultured hepatocytes of rat.
• EFFECT OF CARBAMATES ON RAT HEPATOCYTES IN THE PRIMARY CULTURE
• EFFECT OF CARBAMATES ON RAT FRESHLY ISOLATED HEPATOCYTES
• Collaborative work on evaluation of ovarian toxicity by repeated-dose and fertility studies in female rats
• Gene Expression Property of High-Density Three-Dimensional Tissue of HepG2 Cells Formed in Radial-Flow Bioreactor(BIOINFORMATICS)
• Three-Dimensional High-Density Culture of HepG2 Cells in a 5-ml Radial-Flow Bioreactor for Construction of Artificial Liver(Biochemical Engineering)
• 日本人で新たに見いだされた低活性型CYP2D6ハプロタイプ
• Morphological characterization of the ovary under normal cycling in rats and its viewpoints of ovarian toxicity detection
• Safety assessment of biopharmaceuticals : Japanese perspective on ICH S6 guideline maintenance
• CURRENT OPINION : SAFETY EVALUATION OF DRUG METABOLITES IN DEVELOPMENT OF PHARMACEUTICALS
• Development of the inclusive evaluation method for the percutaneous absorption III : Prediction of human dermal concentration of chemicals in various vehicles
• Prediction of skin permeability of compounds from their molecular structure
• CYP3A4 Gene Polymorphisms Influence Testosterone 6β-hydroxylation
• Results of a Japanese ring study of a Human Cell Line Activation Test (h-CLAT) for predicting skin sensitization potential (1st report)
• P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
• COLLABORATIVE WORK TO EVALUATE TOXICITY ON MALE REPRODUCTIVE ORGANS BY REPEATED DOSE STUDIES IN RATS : OVERVIEW OF THE STUDIES
• Ethnic Differences in Genetic Polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1
• Bodyweight change during the first 5 days of chemotherapy as an indicator of cisplatin renal toxicity
• Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production
• Role of TNF-α and extracellular ATP in THP-1 cell activation following allergen exposure
• Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO_4
• Role of mitogen-activated protein kinase in CD86/CD54 expression induced by contact sensitizers on THP-1 cells
• The response pattern of THP-1 cells to allergens and mechanisms of allergen-induced THP-1 cell activation
• Problems with Registration-Directed Clinical Trials for Lung Cancer in Japan
• Phase I study of cisplatin, vinorelbine, and concurrent thoracic radiotherapy for unresectable stage III non-small cell lung cancer
• Tumor response to chemotherapy : The validity and reproducibility of RECIST guidelines in NSCLC patients
• Prospective Evaluation of the Feasibility of Cisplatin-based Chemotherapy for Elderly Lung Cancer Patients with Normal Organ Functions
• 21C-01-3 Genetic polymorphisms of carcinogen-activating human phenol sulfotransferase and arylamine n-acetyltransferase, and urothelial cancer susceptibiltiy.
• Effects of pre-culture conditions on the human Cell Line Activation Test (h-CLAT) results : Results of the 4^ Japanese inter-laboratory study
• A study on serum difference on test results in the human Cell Line Activation Test (h-CLAT) : Results of 3^ Japanese inter-laboratory study
• A Study of the Criteria for Selection of THP-1 Cells in the Human Cell Line Activation Test (h-CLAT) : Results of 2^ Japanese Inter-laboratory Study
• Review of an alternative to animal testing for safety evaluation of cosmetic ingredients using Quasi-drug : Skin permeation and absorption test task force
• Review of an alternative to animal testing for safety evaluation of Quasi-drug
• Effect of Estradiol and Nonyiphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos
• Suppressive Effect of p-Nonylphenol on Male-Specific mRNA Expression in the Embryonic Gonad of Chickens
• Effect of Estradiol and Nonylphenol on mRNA Levels of VitellogeninII in the Liver of Chicken Embryos
• Development of alternative method for eye irritation test using gel embedded culture method
• The influence of light source and cell line on in vitro phototoxicity tests
• Investigation of co-stimulatory molecules expression and cytokines production in THP-1 human monocyte cell line treated with skin sensitizers
• Skin sensitization test with human monocytic leukemia cell line in fragrances
• Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
• Long-term follow-up of patients with unresectable locally advanced non-small cell lung cancer treated with chemoradiotherapy: A retrospective analysis of the data from the Japan Clinical Oncology Group trials (JCOG0003A)
• STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
• EFFECTS ON FETAL GROWTH OF REPEATED BLOOD COLLECTION FOR TOXICOKINETICS FROM PREGNANT RATS
• Classification for skin sensitization potency using human Cell Line Activation Test (h-CLAT)
• Evaluation of h-CLAT (in vitro skin sensitization test) based on 100 known chemicals
• Genetic Polymorphisms of Copper- and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
• Recent Trends of Alternative Methods to Phototoxicity Testing in Japan
• "B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
• Evaluation of eye irritation potential of 114 chemicals and correspondence to GHS classification using in vitro Short Time Exposure (STE) test
• An inter-laboratory study of Short Time Exposure (STE) test for predicting eye irritation potential of personal care products
• Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer
• Pharmacokinetic Study of Tris (2-chloroethyl) phosphate (TCEP) After Inhalation Exposure (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
• "B-1 Pharmacokinetic Study Of Tris(2-chloroethyl)phosphate (TCEP) in Rats After inhalation.
• LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
• MORPHINE METABOLISM IN ISOLATED HEPATOCYTES AND ITS IMPLICATIONS FOR HEPATOTOXICITY
• STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
• COMPARATIVE TOXICOKINETIC STUDY OF RUBBER ANTIOXIDANTS, 2-MERCAPTOBENZIMIDAZOLE AND 2-MERCAPTOMETHYLBENZIMIDAZOLE, BY SINGLE ORAL ADMINISTRATION IN RATS
• 22D-11-3 Increased Liver and Kidney Toxicities in Rats Caused by Co-administration of 2-Mercaptobenzimidazole (MBI) and Lipopolysaccharide (LPS) and Their Toxicokinetics (TK).
• Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
• Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
• 2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
• 2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
• STUDIES ON THE ESTABLISHMENT OF APPROPRIATE SPERMATOGENIC ENDPOINTS FOR MALE FERTILITY DISTURBANCE IN RODENT INDUCED BY DRUGS AND CHEMICALS I. NITROBENZENE
• Study on optimization of in vitro sensitization assay using THP-1 cells
• Evaluation of Drug-metabolizing Capacities of Cell Lines Using for Alternative Tests : with Special Reference to Alterenative Sensitization Test
• Application of in vitro cytotoxicity test for alternative method to systemic toxicity in vivo : metabolic activation system and treatment period
• Induction of oral tolerance and desensitization to propolis contact sensitivity in guinea pigs
• Development of an in vitro skin sensitization test (human Cell Line Activation Test ; h-CLAT) using THP-1 cell (human monocytic leukemia cell line)
• The Forefront of Alternatives to Animal Testing : the Search for a Breakthrough in In Vitro Toxicology
• Cell-based in vitro skin sensitization methods
• In vitro skin sensitization test
• The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells
• Contribution of ICH on 3Rs in alternatives to animal experiments
• Toxicological bases for micro-dose study(Toxicological Bases for Micro-dose Study, Proceedings of the 32nd Annual Meeting)
• Significance of Japanese Center for the Validation of Alternative Methods (JaCVAM) Establishment
• Intrductory Remarks : REPEATED DOSE TISSUE DISTRIBUTION STUDIES (Repeated dose tissue distribution studies
• The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (7^ Report) : Evaluation of Volatile, Poorly Soluble Fragrance Materials
• The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (6^ Report) : A Study for Evaluating Oxidative Hair Dye Sensitization Potential Using h-CLAT
• The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (5^ Report) : A Study for Evaluating Preservative Skin Sensitization Potential Using h-CLAT
• A tiered approach combining the short time exposure (STE) test and the bovine corneal opacity and permeability (BCOP) assay for predicting eye irritation potential of chemicals
• Evaluation of DNA microarray results in the Toxicogenomics Project (TGP) consortium in Japan

もっと見る 閉じる

スポンサーリンク