Evaluation of h-CLAT (in vitro skin sensitization test) based on 100 known chemicals
スポンサーリンク
概要
- 論文の詳細を見る
- 2008-12-31
著者
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Sakaguchi Hitoshi
Safety Science Research Laboratories, Kao Corporation
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Itagaki Hiroshi
Shiseido Research Center
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Itagaki Hiroshi
Shiseido Safety And Analytical Research Center
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Ashikaga Takao
Shiseido Co. Ltd.
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Ashikaga Takao
Shiseido Safety And Analytical Research Center
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Kosaka Nanae
Kao Corporation, Safety Science Research Laboratories
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Sakaguchi Hitoshi
Kao Corporation, Safety Science Research Laboratories
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Nishiyama Naohiro
Kao Corporation, Safety Science Research Laboratories
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SONO Sakiko
Shiseido Co., Ltd.
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Nishiyama Naohiro
Kao Corporation
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Sakaguchi Hitoshi
Kao Corporation
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Itagaki Hiroshi
Shiseido Co. Ltd.
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Nukada Yuko
Kao Corporation
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Ito Yuichi
Kao Corporation
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Sono Sakiko
Shiseido Co. Ltd.
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Kosaka Nanae
Kao Corporation
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NUKADA Yuuko
Kao Corporation
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ITOU Yuuichi
Kao Corporation
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Suzuki Hiroyuki
Kao Corporation Product Quality Management Division
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Itagaki Hiroshi
Safety And Analytical Research Center Shiseido Co. Ltd.
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Itagaki Hiroshi
Lion Corporation
関連論文
- Assessment of the human Cell Line Activation Test (h-CLAT) for Skin Sensitization ; Results of the First Japanese Inter-laboratory Study
- Inter-laboratory study of short time exposure (STE) test for predicting eye irritation potential of chemicals and correspondence to globally harmonized system (GHS) classification
- Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone
- Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1 : Possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate
- Development of the inclusive evaluation method for the percutaneous absorption III : Prediction of human dermal concentration of chemicals in various vehicles
- Prediction of skin permeability of compounds from their molecular structure
- Results of a Japanese ring study of a Human Cell Line Activation Test (h-CLAT) for predicting skin sensitization potential (1st report)
- Production of IL-8 in THP-1 cells following contact allergen stimulation via mitogen-activated protein kinase activation or tumor necrosis factor-α production
- Role of TNF-α and extracellular ATP in THP-1 cell activation following allergen exposure
- Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO_4
- Role of mitogen-activated protein kinase in CD86/CD54 expression induced by contact sensitizers on THP-1 cells
- The response pattern of THP-1 cells to allergens and mechanisms of allergen-induced THP-1 cell activation
- Effects of pre-culture conditions on the human Cell Line Activation Test (h-CLAT) results : Results of the 4^ Japanese inter-laboratory study
- A study on serum difference on test results in the human Cell Line Activation Test (h-CLAT) : Results of 3^ Japanese inter-laboratory study
- A Study of the Criteria for Selection of THP-1 Cells in the Human Cell Line Activation Test (h-CLAT) : Results of 2^ Japanese Inter-laboratory Study
- Review of an alternative to animal testing for safety evaluation of Quasi-drug
- Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone
- Classification for skin sensitization potency using human Cell Line Activation Test (h-CLAT)
- Evaluation of h-CLAT (in vitro skin sensitization test) based on 100 known chemicals
- Evaluation of eye irritation potential of 114 chemicals and correspondence to GHS classification using in vitro Short Time Exposure (STE) test
- 2B-06 In vitro alternatives to skin irritation test: Determination for gene expression of pro-inflammatory cytokine.
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- Development of in vitro alternative assays for acute systemic toxicity, and skin genotoxicity test in vivo
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- Evaluation of changes of cell surface thiols as a new biomarker for in vitro sensitization (I) : The accuracy of in vitro assay vs. in vivo assay
- Study on optimization of in vitro sensitization assay using THP-1 cells
- Evaluation of Drug-metabolizing Capacities of Cell Lines Using for Alternative Tests : with Special Reference to Alterenative Sensitization Test
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- Study on the reliability and reproducibility of visual assessment for human skin irritation test
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- Induction of oral tolerance and desensitization to propolis contact sensitivity in guinea pigs
- Low-molecular Peptide Model of Protein Denaturation by UVA Irradiation and the Effect of Antioxidants
- Development of an in vitro skin sensitization test (human Cell Line Activation Test ; h-CLAT) using THP-1 cell (human monocytic leukemia cell line)
- The Forefront of Alternatives to Animal Testing : the Search for a Breakthrough in In Vitro Toxicology
- Cell-based in vitro skin sensitization methods
- In vitro skin sensitization test
- The relationship between CD86 and CD54 protein expression and cytotoxicity following stimulation with contact allergen in THP-1 cells
- A Strategic Approach for Predicting Phototoxicity of Cosmetic Ingredients
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (7^ Report) : Evaluation of Volatile, Poorly Soluble Fragrance Materials
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (6^ Report) : A Study for Evaluating Oxidative Hair Dye Sensitization Potential Using h-CLAT
- The Japanese Ring Study of a Human Cell Line Activation Test (h-CLAT) for Predicting Skin Sensitization Potential (5^ Report) : A Study for Evaluating Preservative Skin Sensitization Potential Using h-CLAT
- A tiered approach combining the short time exposure (STE) test and the bovine corneal opacity and permeability (BCOP) assay for predicting eye irritation potential of chemicals