Tier system using monolayer culture of SIRC cells and three-dimensional dermal model for eye irritancy assessment
スポンサーリンク
概要
- 論文の詳細を見る
- 2008-12-31
著者
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Kitagaki Masato
Shiseido Research Center
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Hagino Shigenobu
Shiseido Research Center
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Itagaki Hiroshi
Shiseido Research Center
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Itagaki Hiroshi
Shiseido Co. Ltd.
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OKAZAKI Yuuko
Shiseido Quality Assessment Center
関連論文
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- Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1 : Possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate
- Development of the inclusive evaluation method for the percutaneous absorption III : Prediction of human dermal concentration of chemicals in various vehicles
- Review of an alternative to animal testing for safety evaluation of Quasi-drug
- Changes of cell-surface thiols and intracellular signaling in human monocytic cell line THP-1 treated with diphenylcyclopropenone
- Classification for skin sensitization potency using human Cell Line Activation Test (h-CLAT)
- Evaluation of h-CLAT (in vitro skin sensitization test) based on 100 known chemicals
- 2B-06 In vitro alternatives to skin irritation test: Determination for gene expression of pro-inflammatory cytokine.
- Tier system using monolayer culture of SIRC cells and three-dimensional dermal model for eye irritancy assessment
- SIRC-CVS CYTOTOXICITY TEST : AN ALTERNATIVE FOR PREDICTING RODENT ACUTE SYSTEMIC TOXICITY
- QUANTITATIVE MEASUREMENT OF SPLICED XBP1 mRNA AS AN INDICATOR OF ENDOPLASMIC RETICULUM STRESS
- Development of in vitro alternative assays for acute systemic toxicity, and skin genotoxicity test in vivo
- Evaluation of changes of cell surface thiols as a new biomarker for in vitro sensitization assay (II) : the comparison between cell lines
- Evaluation of changes of cell surface thiols as a new biomarker for in vitro sensitization (I) : The accuracy of in vitro assay vs. in vivo assay
- Study on optimization of in vitro sensitization assay using THP-1 cells
- Evaluation of Drug-metabolizing Capacities of Cell Lines Using for Alternative Tests : with Special Reference to Alterenative Sensitization Test
- The cross-link between the reduced cell surface thiols and the oxidized GSH/GSSG ratio in monocyte-derived dendritic cells treated with haptens
- Study on the reliability and reproducibility of visual assessment for human skin irritation test
- Low-molecular Peptide Model of Protein Denaturation by UVA Irradiation and the Effect of Antioxidants
- The Forefront of Alternatives to Animal Testing : the Search for a Breakthrough in In Vitro Toxicology
- A Strategic Approach for Predicting Phototoxicity of Cosmetic Ingredients