Ohno Yasuo | National Institute of Health Sciences

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著作論文

Assessment of the human Cell Line Activation Test (h-CLAT) for Skin Sensitization ; Results of the First Japanese Inter-laboratory Study
Collaborative work on evaluation of ovarian toxicity by repeated-dose and fertility studies in female rats
Morphological characterization of the ovary under normal cycling in rats and its viewpoints of ovarian toxicity detection
Safety assessment of biopharmaceuticals : Japanese perspective on ICH S6 guideline maintenance
CURRENT OPINION : SAFETY EVALUATION OF DRUG METABOLITES IN DEVELOPMENT OF PHARMACEUTICALS
Results of a Japanese ring study of a Human Cell Line Activation Test (h-CLAT) for predicting skin sensitization potential (1st report)
P-103 Collaborative Work to Evaluate Toxicity on Male Reproductive Organs by A 2-Week Repeated-Dose Toxicity Study in Rats : 29)Summary.(Proceedings of the 27th Annual Meeting)
Effects of pre-culture conditions on the human Cell Line Activation Test (h-CLAT) results : Results of the 4^ Japanese inter-laboratory study
A study on serum difference on test results in the human Cell Line Activation Test (h-CLAT) : Results of 3^ Japanese inter-laboratory study
A Study of the Criteria for Selection of THP-1 Cells in the Human Cell Line Activation Test (h-CLAT) : Results of 2^ Japanese Inter-laboratory Study
JaCVAM statement on new alternatives to animal testing
Review of an alternative to animal testing for safety evaluation of Quasi-drug
"C-5 Validation of alternatives to eye irritation tests for cosmetic ingredients (Results of the first, second, and third validation).
The Second Phase Validation Study of Alternative Methods to The Eye Irritation Test 11)Evaluation of EYTEX.
THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 10)EVALUATION OF CYTOTOXICITY TEST ON CHL CELLS
THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHOD TO THE EYE IRRITATION TEST 8.Evaluation of Cytotoxicity Test in SIRC Cells
The second phase validation study of alternative methods to the eye irritation test (4) Evaluation of hemoglobin denaturation tests.
The second phase validation study of alternative methods to the eye irritation test : Evaluation of Skin-squared ZK1100 and ZK1200 Models
The second-phase validation of alternative methods to the eye irritation test. 9) Evaluation of cytotoxicity test on HeLa cells.
THE SECOND PHASE OF VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 7) EVALUATION OF CYTOTOXICITY TESTS WITH Cornepack
The second phase validation study of alternative methods to the eye irritation test (6)Evaluation of MATREX ^
The second phase validation study of alternative methods to the eye irritation test for cosmetic ingredients 3) Evaluation of Hemolysis test.
The second phase validation study of alternative methods to the eye irritation test (2) Evaluation of chorioallantoic membrane (CAM) tests.
Results from Draize eye-irritation test and implications of their variations.
Validation of alternative methods to eye irritaion test for safety evaluation of cosmetic ingredients, project and progress.
Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. I. : Measurement of the amount of nitrosamine formed in rat and guinea pig stomachs.
"B-3 Toxicokinetic Study of 2-Mercaptobenzimidazole (MBI) and its Methylated Derivative (MMBI) in Rats after Single Oral-Dose Administration.
Pharmacokinetic Study of Tris (2-chloroethyl) phosphate (TCEP) After Inhalation Exposure (Proceedings of the 22nd Symposium on Toxicology and Environmental Health)
"B-2 Metabolic Study of Tris(2-Chloroethyl) Phosphate (TCEP) in vivo and in vitro.
"B-1 Pharmacokinetic Study Of Tris(2-chloroethyl)phosphate (TCEP) in Rats After inhalation.
LOSS OF VIABILITY AFTER DISULFIRAM TREATMENT WITHOUT PRECEDING DEPLETION OF INTRACELLULAR GSH
MORPHINE METABOLISM IN ISOLATED HEPATOCYTES AND ITS IMPLICATIONS FOR HEPATOTOXICITY
STUDIES ON NITROSAMINE FORMATION BY THE INTERACTION BETWEEN DRUGS AND NITRITE. II. : Hepatotoxicity by the simultaneous administration of several drugs and nitrite.
Comparison of Thyroid Toxicity and Toxicokinetics of 2-Mercapto-4-methylbenzimidazole (4MeMBI) and its 5-Methyl Isomer (5MeMBI), Rubber antioxidant, in Rats by Single and Repeated Oral-Dose Administrations
Endogenous Nitric Oxide Formation Stimulated by LPS in Hypothyroid Rats Induced by 2-Mercaptobenzimidazole (MBI)
2C-13 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration - Metabolism and urinary Excretion
2C-12 Toxicokinetic Study of 2-Mercapto-benzimidazole(MBI) and its Methylated Derivative (MMBI) in Rats Treated by Repeated Oral Administration.
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy
Application of in vitro cytotoxicity test for alternative method to systemic toxicity in vivo : metabolic activation system and treatment period
Contribution of ICH on 3Rs in alternatives to animal experiments
Toxicological bases for micro-dose study(Toxicological Bases for Micro-dose Study, Proceedings of the 32nd Annual Meeting)
Intrductory Remarks : REPEATED DOSE TISSUE DISTRIBUTION STUDIES (Repeated dose tissue distribution studies
Evaluation of DNA microarray results in the Toxicogenomics Project (TGP) consortium in Japan

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