ENHANCEMENT OF INTESTINAL TUMOR INDUCTION BY LOW DOSE COMBINATIONS OF HETEROCYCLIC AMINES IN A MULTI-ORGAN CARCINOGENESIS BIOASSAY

スポンサーリンク

概要

• 論文の詳細を見る
• 日本トキシコロジー学会の論文
• 1993-11-25

著者

• Hagiwara A

  Dims Institute Of Medical Science Inc.

• Hagiwara Akihiro

  Dims医科学研究所

• KAWABE Mayumi

  DIMS Institute of Medical Science, Inc.

• Kawabe Mayumi

  Dims Inst. Of Medical Sci. Inc.

• Kawabe Mayumi

  名古屋市立大学 医学研究科第一病理学

• Kawabe Mayumi

  Dims Inst. Medical Sci. Inc.

• Kawabe Mayumi

  三省製薬

• Kuribayashi Masanori

  名古屋市立大学 医学研究科実験病態病理学分野

• Tanaka H

  Daiyu-kai Institute Of Medical Science

• HAGIWARA Akihiro

  1st, Dept. Pathol., Nagoya City Univ. Med. Sch.

• HASEGAWA Ryouhei

  1st, Dept.Pathol., Nagoya City Univ.Med.Sch.

• Hasegawa Ryouhei

  1st Dept.pathol. Nagoya City Univ.med.sch.

• TANAKA Hikaru

  1st, Dept.Pathol., Nagoya City Univ.Med.Sch.

• KAWABE Mayumi

  1st, Dept.Pathol., Nagoya City Univ.Med.Sch.

• SHIRAI Tomoyuki

  1st, Dept.Pathol., Nagoya City Univ.Med.Sch.

• Hagihara Atsushi

  Department Of Pathology Osaka City University Medical School

• Hagiwara Akihiro

  First Department Of Pathology Nagoya City University Medical School

関連論文

• A twenty eight-day repeated dose toxicity study of black soybean extract in Sprague-Dawley rats
• LACK OF HINOKITIOL (BETA-THUJAPLICIN) CARCINOGENICITY IN F344/DuCrj RATS
• Close Relation of Transforming Growth Factor-α Positive Hepatic Foci to Hepatocellular Tumor Development in the Rat
• Dose Dependent Promoting Effects of Hexachlorobenzene on Hepatocarcinogenesis in a Rat Medium-Term Liver Bioassay(Carcinogenicity, Proceedings of the 32nd Annual Meeting)
• Evidence of a Threshold Dose for Promotion of Hepatocarcinogenesis by Hexachlorobenzene in a Rat Medium-Term Liver Bioassay
• P6-42 Mouse medium-term skin carcinogenesis bioassay of kojic acid(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
• FOUR-WEEK ORAL TOXICITY STUDY OF 1-CARBOXY-5,7-DIBROMO-6-HYDROXY-2,3,4-TRICHLOROXANTHONE (HXCA), AN IMPURITY OF PHLOXINE B, IN F344 RATS
• Ninety-toxicity study of annatto extract, a natural food color, in rats. (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• LACK OF CARCINOGENIC RISK IN THE PROSTATE WITH TRANSPLACENTAL AND LACTATIONAL EXPOSURE TO BISPHENOL A IN RATS
• Effects of Antioxidant 1-O-Hexy1-2,3,5-trimethylhydroquinone or Ascorbic Acid on Carcinogenesis Induced by Administration of Aminopyrine and Sodium Nitrite in a Rat Multi-organ Carcinogenesis Model
• A 28-day oral toxicity study of fermentation-derived cellulose, produced by Acetobacter aceti subspecies xylinum, in F344 rats
• Combined Chemopreventive Effects of Perilla or Corn Oil and Indomethacin in a Rat Medium-Term Multiorgan Carcinogenesis Model
• Reliability Evaluation of the Mediumterm Liver Bioassay Based on Long-term Feeding Study Results for Phenobarbital with Reference to the Dose-response
• Ninety-day oral toxicity study of rhamsan gum, a natural food thickener produced from Sphingomonas ATCC 31961, in Crl:CD(SD)IGS rats
• Differences in Sensitivity of F344 Rats from Different Breeders to Phenobarbital Hepatocarcinogenicity
• Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis
• CARCINOGENICITY OF DIFOLATAN IN B6C3F_1 MICE
• A DOSE-RELATED INDUCTION OF γ-GT POSITIVE FOCI BY N-NITROSODIMETHYLAMINE IN RAT LIVER IN AN IN VIVO SHORT TERM SYSTEM
• EFFECTS OF PARTIAL HEPATECTOMY AND CARBON TETRACHLORIDE ON THE INDUCTION OF HYPERPLASTIC NODULES IN THE LIVER TREATED WITH N-2-FLUORENYLACETAMIDE
• SACCHARIN-INDUCED HYPERPLASIA OF THE RAT URINARY BLADDER
• EFFECTS OF THE CO-MUTAGEN N0RHARMAN IN RATS (The 6th Meeting for the Study of Toxic Effect)
• HISTOPATHOLOGICAL STUDY OF SUBACUTE EFFECTS OF CARBAZOLE IN MICE (The 6th Meeting for the Study of Toxic Effect)
• SUBACUTE TOXICITY STUDY OF N, N'-DIPHENYL-P-PHENYENEDIAMINE IN RATS (The 6th Meeting for the Study of Toxic Effect)
• PREVENTION BY NATURAL FOOD ANTHOCYANINS, PURPLE SWEET POTATO COLOR AND RED CABBAGE COLOR, OF 2-AMINO- 1 -METHYL-6-PHENYLIMIDAZO [4,5 -b] PYRIDINE (PhIP)-ASSOCIATED COLORECTAL CARCINOGENESIS IN RATS INITIATED WITH 1,2-DIMETHYLHYDRAZINE
• Susceptibility of Four F_1 Hybrids of Male Rats to the Promoting Effects of Sodium L-ascorbate in Two-Stage Urinary Bladder Carcinogenesis
• Dose-dependent Induction of Mammary Carcinomas in Female Sprague-Dawley Rats with 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine
• Inhibitory effects of the phenolic antioxidant 1-0-hexy1-2, 3, 5-trimethylhydroquinone (HTHQ) on heterocyclic amine (HCA)-induced mutagenesis and rat liver carcinogenesis.
• B-26 ORGAN SPECIFIC EFFECT OF TUMOR DEVELOPMENT BY LOW DOSE COMBINATIONS OF MODIFICATION AGENTS IN WIDE-SPECTRUM CARCINOGENESIS MODEL USING F344 RATS
• Decrease of Prostaglandin E_2 and 5-Bromo-2'-deoxyuridine Labeling but Not Prostate Tumor Development by Indomethacin Treatment of Rats Given 3,2'-Dimethyl-4-aminobiphenyl and Testosterone Propionate
• Modification by Analgesics of Lesion Development in the Urinary Tract and Various Other Organs of Rats Pretreated with Dihydroxy-di-N-propylnitrosamine and Uracil
• DOSE-DEPENDENT ENHANCEMENT BY THE HORMONE DEHYDROEPIANDROSTERONE OF DIETHYLNITROSAMINE-INITIATED LIVER FOCI DEVELOPMENT IN F344 MALE RATS
• EVALUATION OF CARCINOGENICITY OF PESTICIDES IN A MEDIUMTERM LIVER CARCINOGENICITY BIOASSAY
• 325 Synergistic Enhancement of Glutathione S-Transferase Placental Form-positive Hepatic Foci Development in Diethylnitrosamine-treated Rats by Combined Administration of Five Heterocyclic Amines at Low Doses
• A07 LACK OF MODIFYING EFFECTS OF 2 OXIDATIVE TYPE HAIR DYES ON INDUCTION OF PRENEOPLASTIC GLUTATHIONE S-TRANSFERASE PLACENTAL FORM POSITIVE FOCI IN A MEDIUM-TERM BIOASSAY SYSTEM USING F344 RATS
• LACK OF MODIFYING EFFECTS OF 2, 2'-[(4-AMINOPHENYL) IMINO] BISETHANOL SULFATE ON INDUCTION OF PRENEOPLASTIC γ-GLUTAMYL TRANSPEPTIDASE-POSITIVE FOCI IN A MEDIUMTERM BIOASSAY SYSTEM USING F344 RATS
• SPONTANEOUS TUMORS IN B6C3F_1 MICE
• ASSAY OF 7 COMPOUNDS FOR PROMOTING POTENTIAL ON THE DEVELOPNENT OF γ-GLUTAMIL TRANSPEPTIDASE-POSITIVE LIVER CELL FOCI IN THE RAT
• CHRONIC TOXICITY STUDIES WITH N,N'-DIPHENYL-P-PHENYLENEDIAMINE IN RATS
• Influence of Strain and Diet on Hepatocarcinogenicity of N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN) in Rats : Slight Inhibition of Preneoplastic Liver Lesion Development by Uracil
• SUBCHRONIC ORAL TOXICITY STUDY WITH MORPHOLINE OLEIC ACID SALT IN B6C3F_1 MICE
• THIRTEEN WEEKS SUBACUTE ORAL TOXICITY STUDY WITH SODIUM ORTHO-PHENYL-PHENATE (OPP-Na) IN B6C3F_1 MICE
• KOJIC ACID-ABSENCE OF TUMOR-INITIATING ACTIVITY IN RAT LIVER, AND OF CARCINOGENIC AND PHOTO-GENOTOXIC POTENTIAL IN MOUSE SKIN
• Annatto extract, a carotenoid natural food color, lacks tumor promoting effects in a medium-term liver carcinogenesis bioassay in rats (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
• 90-day repeated dose toxicity study of gum arabic(General toxicity, Proceedings of the 32nd Annual Meeting)
• LACK OF SIGNIFICANT ALTERATION IN THE PROSTATE OR TESTIS OF F344 RAT OFFSPRING AFTER TRANSPLACENTAL AND LACTATIONAL EXPOSURE TO BISPHENOL A
• RELIABILITY AND PRACTICALITY OF MEDIUM-TERM CARCINOGENESIS BIOASSAYS(WORKSHOP 4 : NEW TECHNOLOGY AND EVALUATIONS OF IN VIVO TOXICITY STUDIES)
• DOSE-RELATED INCREASES IN QUANTITATIVE VALUES FOR GLUTATHIONE S-TRANSFERASE PLACENTAL FORM (GST-P) POSITIVE FOCI AND CYTOCHROME P-450 LEVELS IN THE LIVER OF F344 RATS EXPOSED TO PHENOBARBITAL SODIUM (PB) IN A MEDIUM-TERM BIOASSAY
• Site-specific Effects of Testosterone Propionate on the Prostate of Rat Pretreated with 3,2'-Dimethyl-4-aminobiphenyl : Dose-dependent Induction of Invasive Carcinomas
• Organ-dependent Modifying Effects of Caffeine, and Two Naturally Occurring Antioxidants α-Tocopherol and n-Tritriacontane-16, 18-dione, on 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) -induced Mammary and Colonic Carcinogenesis in Female F344
• "P-33 Inhibition of development of naturally occuring GST-P positive hepatocytic foci in rats chronically treated with phenolic compounds
• DOSE-DEPENDENT INDUCTION OF CARCINOMAS AND GLUTATHIONE S-TRANSFERASE PLACENTAL FORM NEGATIVE EOSINOPHILIC FOCI IN THE RAT LIVER BY DI(2-ETHYLHEXYL)PHTHALATE AFTER DIETHYLNITROSAMINE INITIATION
• MEDIUM-TERM BIOASSAYS AS ALTERNATIVE CARCINOGENICITY TEST
• EFFECTS OF A MIXTURE OF ADI DOSES OF 20 PESTICIDES ON RAT HEPATOCARCINOGENESIS
• INHIBITING EFFECTS OF DIETHYLMALEATE OR NH_4Cl ON NaHCO_3, BUT NOT BUTYLATED HYDROXYANISOLE, PROMOTION OF URINARY BLADDER CARCINOGENESIS IN MALE F344 RATS INITIATED WITH N-BUTYL-N-(4-HYDROXYBUTYL)NITROSAMINE
• 21C-10-5 Effect of Hepatocarcinogenesis of Tamoxifen in the Medium-term Liver Bioassay (Ito Model).
• 3A-07 Muiti-Organ Carcinogenesis Bioassay of Quinoid Madder Colors
• ENHANCEMENT OF INTESTINAL TUMOR INDUCTION BY LOW DOSE COMBINATIONS OF HETEROCYCLIC AMINES IN A MULTI-ORGAN CARCINOGENESIS BIOASSAY
• Low susceptibility of nude mice to induction of invasive urinary bladder cancers by N-Ethyl-N-(4-hydroxybutyl) nitrosamine (EHBN).
• RISK ASSESSMENT OF MIXTURES OF 40 OR 20 PESTICIDES AT ADI DOSES IN A MEDIUM-TERM MULTI-ORGAN CARCINOGENESIS BIOASSAY USING F344 MALE RATS
• DIFFERENT RESPONSE OF PHENOBARBITAL PROMOTION ON THE DEVELOPMENT OF γ-GLUTAMYLTRANSPEPTIDASE-POSITIVE FOCI (γ-GT) IN THE RAT LIVER INITIATED WITH DIETHYLNITROSAMINE (DEN), N-HYDROXY-2-ACETYLAMINOFLUORENE (N-OH-AAF) AND AFLATOXIN B_1 (Af-B_1)
• A11 MODIFYING EFFECTS OF BERAPROST SODIUM ON N-METHYL-N-NITROSOUREA CARCINOGENESIS IN F344 RATS
• P400 CAN THE MAP TECHNIQUE BE APPLIED TO DETECT DELAYED AFTERDEPOLARIZATION ? : ELECTROPHYSIOLOGICAL AND PHARMACOLOGICAL EVIDENCE
• 0901 EFFECT OF A CLASS III ANTIARRHYTHMIC DRUG ON REFRATORY PERIOD. : DEMONSTRATION OF REVERSE USE DEPENDENCY ASSESSED BY MONOPHASIC ACTION POTENTIALS.
• -P159- Effects of Sodium and Calcium Channel Blockers on Monophasic Action Potential(MAP)Recordings Assessed by the Canine Isolated, Blood-Perfused Ventricular Tissue Preparation(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATIO
• -P157- Electrophysiological and Pharmacological Characteristics of Digitalis-induced Triggered Activity in the Canine Isolated, Blood-perfused Ventricular Muscle Preparation.(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SO
• 239 RATS WIDE-SPECTRUM INITATION MUTIPLE ORGAN BIOASSAY MODELS FOR ASSESSING MODIFYING EFFECTS IN NONHEPATOCARCINGENS
• 223 Modifying Effects of Hepatocarcinogens or Antioxidants on Preneoplastic and Neoplastic Lesion Development in a Multi-organ Carcinogenesis Bioassay Using F344 Rats.
• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
• Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
• Lack of Tumor Promoting Effects of Carrageenan on 1,2-Dimethylhydrazine-induced Colorectal Carcinogenesis in Male F344 Rats
• A Complete Response Induced by 21-day Sorafenib Therapy in a Patient with Advanced Hepatocellular Carcinoma
• No Promoting Effect of Ethyl Tertiary-butyl Ether (ETBE)on Rat Urinary Bladder Carcinogenesis Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine
• LACK OF COMBINATION HEPATOCARCINOGENICITY OF HARMAN, NORHARMAN AND AMITROLE WHEN GIVEN WITH NaNO_2 IN THE RAT
• Inhibitory potency of tacrolimus ointment on skin tumor induction in a mouse model of an initiation-promotion skin tumor

もっと見る 閉じる

スポンサーリンク