患者が入手できる一般書籍の有用性と信頼性における問題点の検討

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We examined the utility and reliability of data consisting of general information about drug characteristics, contraindications and adverse drug reactions (ADRs) in drug guidebooks which are available to patients in bookstores. The information for patients written in five drug guidebooks describing prescription drugs was compared with those available in package inserts. The descriptions about warnings were also compared with those on respective package inserts of the drugs themselves, to determine whether the documentation was appropriate. About 9,000-10,000 drugs are contained in these books, with revision being made almost every year. Relatively cheap prices allow easier access of patients to these books. Out of 61 drugs with provisions on warnings, 35 drugs partially or completely lacked an adequate description about the warnings. Approximately 70% of these warnings were related to serious ADRs. These were some insufficient examples in terms of explanations about the warnings (For example, the initial symptoms of the ADRs were either not described or ADRs were explained with medical terms.). As a result of comparing drug guidebooks specific for patients, the number of drugs included, the frequency of revision and the prices are all considered reasonable. It is conceivable that the utility of these drug guidebooks would be greatly improved if the headlines for every descriptions of drugs are more detailed. As for drugs with a potential to induce serious ADRs, the initial symptoms should be described using simple words so that patients can understand them easily, whereby the patients themselves can easily perceive signs of ADRs even at early stages. In addition, adequate guidance is required to cope with the onset of initial ADRs, for example, recommending a prompt discontinuation of drug administration followed by consultations with physicians.
日本医療薬学会の論文
2002-04-10

患者が入手できる一般書籍の有用性と信頼性における問題点の検討

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