Ultrasonographic evaluation of portal vein hemodynamics in experimentally bile duct ligated dogs

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概要

• 論文の詳細を見る

• The purpose of this study was to evaluate the relationship between the results of laboratory examinations and ultrasonographic findings, especially portal vein hemodynamics in experimentally bile duct ligated dogs. Biliary obstruction was accomplished by surgically occluding the common bile duct in five dogs. All the dogs became visibly jaundiced within 24 hours after surgery. The total protein and albumin/globulin ratio showed a gradual decrease throughout the examination period, while blood urea nitrogen reached its peak in the 6th week and decreased to pre ligation values by the 10th week. Similar trends were noted in the alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, and direct and total bilirubin. Total cholesterol and fasting serum bile acid levels rapidly increased after surgery to peak values between the 2nd and 4th week, and then gradually decreased, but still remained high throughout the experiment period. The portal flow volume and velocity significantly (p<0.05) decreased while only a slight increase was noted in the congestion index after bile duct ligation. The cross sectional area of the portal vein changed insignificantly. Bile duct and gallbladder distention was evident within the 1st week after ligation but there was little change in the echogenicity of the liver parenchyma. The results of this study suggest that the determination of Doppler ultrasound parameters of hepatic hemodynamics, especially the portal vein flow indices, may contribute to a better noninvasive assessment of the canine patient with biliary obstructive disease.

• 北海道大学の論文
• 1998-02-27

著者

• Mwanza Timothy

  北海道大学大学院獣医研究科診断治療学講座獣医外科学教室

• Mwanza T

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Mwanza Timothy

  北海道大学 大学院

• Mwanza Timothy

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Timothy Mwanza

  北海道大学 大学院 診断治療

• MIYAMOTO Toru

  Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Vet

• OKUMURA Masahiro

  Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Vet

• KADOSAWA Tsuyoshi

  Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Vet

• FUJINAGA Toru

  Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Vet

• Fujinaga T

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Fujinaga Toru

  Hokkaido Univ. Sapporo Jpn

• Fujinaga Toru

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Okumura Masahiro

  Hokkaido Univ. Hokkaido Jpn

• Okumura Masahiro

  Laboratories Of Veterinary Surgery Graduate School Of Veterinary Medicine Hokkaido University

• Kadosawa Tsuyoshi

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Kadosawa Tsuyoshi

  Department Of Small Animal Clinical Sciences School Of Veterinary Medicine Rakuno Gakuen University

• Miyamoto Toru

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• Okumura M

  Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter

• KADOSAWA Tsuyoshi

  Laboratory of Veterinary Clinical Oncology, Small Animal Clinical Sciences, Graduate School of Veterinary Medicine, Rakuno Gakuen University, 582 Midorimachi, Bunkyodai, Ebetsu, Hokkaido 069–8501, Japan

• KADOSAWA Tsuyoshi

  Laboratory of Veterinary Clinical Oncology, Small Animal Clinical Sciences, Graduate School of Veterinary Medicine, Rakuno Gakuen University

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