MITOGENIC RESPONSIBILITIES OF LYMPHOCYTES IN CANINE BABESIOSIS AND THE EFFECTS OF SPLENECTOMY ON IT
スポンサーリンク
概要
- 論文の詳細を見る
In order to clarify the mechanisms of immune-responses in canine babesiosis, mitogen-induced transformation of lymphocytes from peripheral blood and its relation to parasitemia were chiefly examined in both intact and splenectomized dogs suffering from Babesia gibsoni. The lymphocyte responses to PHA-P, Con A and PWM in dogs infected with B. gibsoni were all extremely depressed as the parasite increased in their peripheral blood. The lymphocyte responses to the mitogens greatly decreased after splenectomy in both groups infected and noninfected with B. gibsoni. Furthermore, severe relapse of parasitemia appeared in the infected dogs after splenectomy. Mild parasitemia and moderate anemia were prolonged for at least 3 months with a high serum IFA titer to the parasite in splenectomized dogs.
- 北海道大学の論文
- 1987-01-30
著者
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Maede Yoshimitsu
Department Of Veterinary Internal Medicine Faculty Of Veterinary Medicine Hokkaido University
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KAWAMURA Masahiro
Department of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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NAMIOKA Shigeo
Department of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
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Maede Yoshimitsu
Department Of Internal Medicine Faculty Of Veterinary Medicine
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Namioka Shigeo
Department Of Laboratory Animal Science Faculty Of Veterinary Medicine Hokkaido University
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Kawamura Masahiro
Department Of Pharmacology Department Of Internal Medicine Jikei University School Of Medicine
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Kawamura Masahiro
Department Of Pharmacology (1) The Jikei University School Of Medicine
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