Effect of Volatile Anesthetics on Steroidogenesis in Isolated Bovine Adrenocortical Fasciculata Cells
スポンサーリンク
概要
- 論文の詳細を見る
To examine effects of volatile anesthetics (VAs) on steroidogenesis, cell suspensions of isolated bovine adrenocortical cells were incubated with several steroidogenic agents in the presence or absence of halothane and sevoflurane. The adrenocortical cells were dispersed by trypsin digestion of bovine adrenal cortex. The cortisol level was measured fluorometrically. VAs inhibited adrenocorticotropic hormone-, acetylcholine-, angiotensin-II-, and KCl-stimulated steroidogenesis in a concentration-dependent manner with extracellular Ca2+. However, dibutyryl cyclic adenosine monophosphate-stimulated steroidogenesis was not inhibited by VAs. These results suggest that VAs inhibit steroidogenesis by blocking Ca2+-influx from the extracellular space without influencing the action of intracellular cyclic nucleotides.
- 社団法人 日本薬理学会の論文
- 2003-10-01
著者
-
Yamazaki Koji
Department of Cardiology, Saitama Cardiovascular and Respiratory Center
-
KAWAMURA Masahiro
Department of Veterinary Internal Medicine, Faculty of Veterinary Medicine, Hokkaido University
-
Shoji K
Department Of Anesthesiology Jikei University School Of Medicine
-
Yamazaki Koji
Department Of Cardiology Saitama Cardiovascular And Respiratory Center
-
Shoji Kazuhiro
Department Of Anesthesiology Jikei University School Of Medicine
-
Saito Hirokazu
Department Of Anesthesiology Jikei University School Of Medicine
-
MASAKI Eiji
Department of Anesthesiology, Jikei University School of Medicine
-
Masaki Eiji
Department Of Anesthesiology Jikei University School Of Medicine
-
Kawamura Masahiro
Department Of Pharmacology Jikei University School Of Medicine
-
Kawamura Masahiro
Department Of Pharmacology Department Of Internal Medicine Jikei University School Of Medicine
-
Yamazaki Koji
Department Of Internal Medicine Jikei University School Of Medicine
-
Yamazaki Koji
Department Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine Kas
-
Kawamura Masahiro
Department Of Pharmacology (1) The Jikei University School Of Medicine
関連論文
- PJ-366 Initial Results and Mid-term Outcomes of Sirolimus-eluting Stent in Acute Coronary Syndrome(Coronary revascularization, PCI-17 (IHD) PJ62,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-143 Differential Predictors for Binary Restenosis between Bare Metal Stents and Sirolimus-Eluting Stent (Cypher)(Coronary revascularization, PCI-6 (IHD) OJ24,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- OJ-143 Differential Predictors for Binary Restenosis between Bare Metal Stents and Sirolimus-Eluting Stent (Cypher)(Coronary revascularization, PCI-6 (IHD) OJ24,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
- Isolation of Vibrio sp.S-1 Exhibiting Extraordinarily High Catalase Activity
- Cytochrome c-552 from Gram-Negative Alkaliphilic Pseudomonas alcaliphila AL15-21T Alters the Redox Properties at High pH
- Cytochrome c and Bioenergetic Hypothetical Model for Alkaliphilic Bacillus spp.
- PJ-705 Usefulness of Inferior Vena Cava Filter for Prevention of Pulmonary Embolism in Patients with Deep Vein Thrombosis(Pulmonary circulation-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-430 Characteristics of Very Elderly Patients with Acute Heart Failure : Comparison with Young Adult Patients(Heart failure, clinical(11)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Randomly Amplified Polymorphic DNA (RAPD) for Rapid Identification of the Spoilage Bacterium Alicyclobacillus acidoterrestris
- Chemical and Microbiological Characteristics of Sardine Meal Fermented with Aspergillus oryzae IFO 4202
- OE-385 Efficacy of Post-stress Early Diastolic Filling Rate Derived from ECG-gated Myocardial Perfusion SPECT to Identify Severe Coronary Artery Disease(OE65,Nuclear Cardiology (Coronary, Myocardium) 1 (I),Oral Presentation (English),The 73rd Annual Scien
- Slowly Progressive Adenocarcinoma of the Lung : Report of a Case
- Changes in the Testicular Damage Caused by Indium Arsenide and Indium Phosphide in Hamsters during Two Years after Intratracheal Instillations
- Long Term Pulmonary Toxicity of Indium Arsenide and Indium Phosphide Instilled Intratracheally in Hamsters
- Rib Metastasis Appearing 8 Years After Surgery for Lung Cancer : Report of a Case
- A Sweat-gland Tumor Metastasizing to the Axilla : Report of a Case
- Feasibility trial of adjuvant chemotherapy with paclitaxel and carboplatin after surgical resection in Japanese patients with non-small cell lung cancer : report of the Lung Oncology Group in Kyushu (LOGIK) protocol 0501
- MITOGENIC RESPONSIBILITIES OF LYMPHOCYTES IN CANINE BABESIOSIS AND THE EFFECTS OF SPLENECTOMY ON IT
- Genetic Alteration in Carcinoid Tumors of the Lung
- Cellular Physiology of Rat Cardiac Myocytes in Cardiac Fibrosis : In Vitro Simulation Using the Cardiac Myocyte/Cardiac Non-Myocyte Co-Culture System
- Primary Osteosarcoma of the Lung : A Case Report
- Effect of Volatile Anesthetics on Steroidogenesis in Isolated Bovine Adrenocortical Fasciculata Cells
- Attenuation of nitric oxide-stimulated soluble guanylyl cyclase from the rat brain by halogenated volatile anesthetics
- Re : Nakamura. Implications of the suppression of guanylate cyclase activity by halothane
- Extracellular ATP Potentiates Steroidogenic Effect of Adrenocorticotropic Hormone in Bovine Adrenocortical Fasciculata Cells
- Inhibitory effect of nitric oxide on the metabolism of halogenated volatile anesthetics by cytochrome P-450
- Integrity of Actin-Network Is Involved in Uridine 5'-Triphosphate Evoked Store-Operated Ca^ Entry in Bovine Adrenocortical Fasciculata Cells
- Lung Cancer with p53 Expression and a Solitary Metastasis to the Stomach : A Case Report
- Preoperative Mechanical Bowel Preparation Unnecessary in Patients Undergoing Thoracic Surgery
- CYTOCHROME P-450 CONTAINING PROTEIN-PROTEIN INTERACTIONS IN BOVINE ADRENOCORTICAL MITOCHONDRIA
- Thymoma Arising in a Thymic Cyst
- Pulmonary Metastasis with an Endobronchial Growth Pattern : Report of a Case
- Surgical Outcome of an Anatomical Resection of Clinical Stage IA Non-Small Cell Lung Cancer Assisted with a Video-Thoracoscopy
- Isolation and Identification of Alicyclobacillus acidoterrestris from Acidic Beverages
- Effect of fluoroquinolones on plasma glucose levels in fasted and glucose-loaded mice
- MITOGEN INDUCED TRANSFORMATION OF LYMPHOCYTES IN CANINE BABESIOSIS WITH SPECIAL REFERENCE TO THE EFFECTS OF THE SPLEEN ON IT
- Effect of Clarithromycin on Endogenous Glucocorticoid Levels in Mice
- Thymic Carcinoma Presenting as an Intraluminal Growth into the Great Vessels and the Cardiac Cavity
- Zinc Bromide-Promoted Tosylation of Alcohols Allows Efficient Temperature-Controlled Primary Hydroxy Sulfonylation
- Chondroblastic Osteosarcoma Arising from the Pleura : Report of a Case
- Prognosis and Therapeutic Response According to the World Health Organization Histological Classification in Advanced Thymoma
- Perioperative infusion of dexmedetomidine at a high dose reduces postoperative analgesic requirements : a randomized control trial
- Characteristics of spontaneous calcium oscillations in renal tubular epithelial cells
- Extracellular ATP Stimulates Steroidogenesis in Bovine Adrenocortical Fasciculata Cells via P2 Purinoceptors.
- Diazepam potentiates the corticoidogenic response of bovine adrenal fasciculata cells to dibutyryl cyclic AMP.
- Effect of adrenaline on steroidogenesis in primary cultured bovine adrenocortical cells.
- Procaine inhibits cyclic AMP-induced steroidogenesis in isolated bovine adrenocortical cells.
- Effects of Efforts to Reduce Bronchoscope Damage and Repair Costs
- Protein rotation study of cytochrome P-450 in submitochondrial particles: Effect of KCl and intermolecular interactions with redox partners.