ヘモグロビンの酸化に対する紫外線照射の影響

概要

論文の詳細を見る
The autoxidation of hemoglobin was markedly increased when the solution of hemoglobin was irradiated by ultraviolet (UV) ray under aerobic conditions. The oxidation of hemoglobin was not observed when hemoglobin was irradiated with UV ray under anaerobic conditions. The UV ray induced oxidation of oxyhemoglobin was accelerated in the presence of inositol hexaphosphate, a strong allosteric effector of the protein, but was inhibited by the addition of catalase, and superoxide dismutase. The rate of oxidation of oxyhemoglobin induced by UV irradiation was dependent on the changes in pH, i.e., it was accelerated at acidic pHs. The result suggested that active oxygens produced by UV irradiation may be involved in the oxidation of hemoglobin.
北陸学院短期大学の論文
1987-12-26