<症例>肝内胆管癌と肝内, 総胆管結石の併存をみた1例

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A 69-year-old female was admitted on October 28,1980,because of anorexia, loss of body weight and pain in the right hypochondrium. CT, ERCP and selective celiac angiography revealed intra-hepatic and intracholedochal gallstones and mass in the right hepatic lobe. The patient underwent choledocholithotomy and T tube drainage on November 26,1980,when radical resection of the hepatic tumor (cholangiocarcinoma) was impossible. She expired at the 57th postoperative day. Autopsy revealed intra-hepatic cholangiocarcinoma and hepatolithiasis (calcium bilirubinate stones). Among the hepatolithiasis, so-called primary type of hepatolithiasis is usually associated with multiple disorders of the bile duct. Contrary to the primary type, so-called secondary hepatolithiasis is seldom associated with bile duct malformation. Although liver cirrhosis and hepatitis B are recognized to be responsible for the pathogenesis of hepatoma, there is no distinctive factor to induce cholangiocarcinoma. However, some authors have reported that chronic cholangitis, abnormal composition of bile or thorotrast may provoke cholangiocarcinoma. Although the relationship between the chronic infection in so-called primary hepatolithiasis and the development of cholangiocarcinoma may be comprehensible, so-called secondary hepatolithiasis is considered to be less responsible for or to be unrelated to the pathogenesis of cholangiocarcinoma because of the absence of bile duct disorders.
近畿大学の論文
1982-03-25

<症例>肝内胆管癌と肝内, 総胆管結石の併存をみた1例

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