<原著>川崎病の臨床ウイルス学的検討

概要

論文の詳細を見る
The clinical and virological studies were performed about 24 cases of mucocutaneous lymph node syndrome (MCLS, Kawasaki disease) admitted to Kinki University Hospital between 1979 and 1980. We found the tendency that the outbreak of MCLS converges in certain periods, such as January 1979,from March to May 1979,January 1980,August and October 1980. In six cases, MCLS occurred following the symptoms resembling the gastrocolitis, respiratory tract infections and otitis media. The response of serum antibody titers against mycoplasma pneumoniae, adeno virus, influenza virus and EB virus was noticed in several cases, and the response of the antibody titers against the almost same viruses was seen among the patients in the same periods. Viral cultures of buffy coat leukocytes washed three times with phosphate buffered saline (PBS) were negative in eight cases, but a line of EBNA positive B-lymphoblastoid cell was established from the peripheral leukocytes of the patient whose serum antibody titer against EBV・VCA was negative, whereas the heterophile antibody titers (sheep erythrocyte agglutination titer was 1 : 2^7,normal 1 : 2^4≥; horse erythrocyte agglutination titer was 1 : 2^8,normal 1 : 2^6>) were high and cold hemoagglutination titer was also hith (1 : 2^9,normal 1 : 2^6>).
近畿大学の論文
1981-09-25