<原著>小児の各種腎疾患における尿中蛋白成分の検討

概要

論文の詳細を見る
Clearance of albumin, transferrin, IgG, IgA, IgM and C3 was measured in the urine of 52 patients with various renal diseases, and existence of the fragments and polymers in the urine was investigated at the acute phase of some renal diseases. Acute glomerulonephritis and rapid progressive glomerulonephritis revealed a large excretion of IgA, and the result suggested the high correlation to renal histological damages. A large excretion of IgG was observed in some cases of acute glomerulonephritis, membranoproliferative glomerulonephritis, purpura nephritis and persistent glomerulonephritis, and also we found fragments of IgG, K-chain and L-chain in the urine of some cases, which suggested the functional abnormalities of renal tubuli. High molecular proteins, C3 and IgM, were detected in the urine of acute glomerulonephritis, rapid progressive glomerulonephritis, purpura nephritis. It was considered that former one might be the result of acute inflammatory process and the latter one might be the result of the glomerular damages. There were high correlations between trans RIgG (Cameron) and the steroid responsiveness only in the cases of pure nephrosis.
近畿大学の論文
1980-12-25