<原報>Thiazole 誘導体の研究〔VIII〕 : 2-Thioureidothiazole 誘導体の合成
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In this report, 2-Alkylthioureido-4-butylthiazoles, 2-Alkylthioureido-5-alkylthiazoles and 2-Alkylthioureido-4,5-dimethylthiazoles were synthesized mainly by route [A] method to examine their biological activity and their chelate formation with Ni^<++>, Co^<++>, Cu^<++>, and Pd^<++>. In order to confirm their structure, route [B] method was carried out. These products obtained were identified by Urtraviolet (UV) absorption spectrum, Infrared absorption spectrum (IR) and Mass spectrum (MS). The UV spectra of 4,5-dimethylderivatives [Va-c] were shifted about 5mμ, a typical example is shown in Fig. (1), compared with those of [I] and [II]. Some Mass spectra of typical compound were given in Fig. (IIA-E).
- 共立薬科大学の論文
- 1973-12-25
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