遺伝情報によるショウジョウバエの悪性腫瘍 : I.ショウジョウバエのl(2)gl遺伝子による脳腫瘍の形成と増殖性

概要

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Recessive mutation at the lethal (2) giant larvae (l (2) gl) locus of Drosophila melanogaster cause a complex syndrome, which has as its most striking features the development of malignant neuroblastomas in the larval brain. When the larval neoplasmic brain tissues of late third instar larvae were serially subcultured in female adult hosts, they grew rapidly and killed their hosts in 10 to 15 days. Implanted neoplasmic cells invaded into all the spaces between the organs of the adult abdomen and head parts. Thus, it is reconfirmed that the l (2) gl gene induced strong malignant tumors in Drosophila melanogaster.
大手前大学・大手前短期大学の論文