ULTRASONOGRAPHIC FINDINGS AND OUTCOME IN VERY-LOW-BIRTH-WEIGHT INFANTS

概要

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We investigated the incidence of neurological disabilities and the association between ultrasound (US) findings and outcome in an institute-based cohort of 201 very-low-birth-weight infants between March 1989 and February 1990. The US findings were classified into the following 4 groups. Group A : normal findings ; Group B : mild periventricular hemorrhage (PVH); Group C : PVH with ventricular distension ; Group D : cystic periventricular leukomalacia, infarction, or parenchymal hemorrhage. In 155 survivors, 41 children (26.5%) presented with one or more disabilities and 30 (19.4%) developed cerebral palsy (CP). The 95 children of group A (72.5%) and 17 of group B (63.0%) showed no neurological deficits. On the other hand, 13 children of group C (81.3%) died before 2years of age, and 16 of group D (76.2%) developed CP. There were significant differences among the four groups. In the surviving infants, the presence of group C or D on US accurately predicted CP (91%) and was highly specific (98%). Our data show that US studies provide valuable information on the occurence of CP in VLBW infants. In overall prognosis including death, only two (5.4%) had normal outcome in 37 infants of group C and D.
名古屋市立大学の論文
1999-07-31